STUDIES IN HUMAN IMMUNIZATION AGAINST INFLUENZA : DURATION OF IMMUNITY INDUCED BY INACTIVE VIRUS

The administration to human beings of formalin-killed influenza virus, concentrated from allantoic fluid, resulted in a high order of antibody response within 2 weeks after injection. Even after 1 year the great majority of individuals vaccinated had antibody levels considerably above their prevacci...

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Detalles Bibliográficos
Autores principales: Hirst, G. K., Rickard, E. R., Friedewald, W. F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1944
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135471/
https://www.ncbi.nlm.nih.gov/pubmed/19871414
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author Hirst, G. K.
Rickard, E. R.
Friedewald, W. F.
author_facet Hirst, G. K.
Rickard, E. R.
Friedewald, W. F.
author_sort Hirst, G. K.
collection PubMed
description The administration to human beings of formalin-killed influenza virus, concentrated from allantoic fluid, resulted in a high order of antibody response within 2 weeks after injection. Even after 1 year the great majority of individuals vaccinated had antibody levels considerably above their prevaccination titer for the PR8, Lee, and a current 1943 strain. An investigation of the occurrence of epidemic influenza A in seven widely separated populations, 1 year after vaccination of part of these groups, showed that the attack rate among vaccinated persons was consistently lower than that of control individuals. The average reduction in attack rate was of the order of 35 per cent.
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spelling pubmed-21354712008-04-18 STUDIES IN HUMAN IMMUNIZATION AGAINST INFLUENZA : DURATION OF IMMUNITY INDUCED BY INACTIVE VIRUS Hirst, G. K. Rickard, E. R. Friedewald, W. F. J Exp Med Article The administration to human beings of formalin-killed influenza virus, concentrated from allantoic fluid, resulted in a high order of antibody response within 2 weeks after injection. Even after 1 year the great majority of individuals vaccinated had antibody levels considerably above their prevaccination titer for the PR8, Lee, and a current 1943 strain. An investigation of the occurrence of epidemic influenza A in seven widely separated populations, 1 year after vaccination of part of these groups, showed that the attack rate among vaccinated persons was consistently lower than that of control individuals. The average reduction in attack rate was of the order of 35 per cent. The Rockefeller University Press 1944-10-01 /pmc/articles/PMC2135471/ /pubmed/19871414 Text en Copyright © Copyright, 1944, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hirst, G. K.
Rickard, E. R.
Friedewald, W. F.
STUDIES IN HUMAN IMMUNIZATION AGAINST INFLUENZA : DURATION OF IMMUNITY INDUCED BY INACTIVE VIRUS
title STUDIES IN HUMAN IMMUNIZATION AGAINST INFLUENZA : DURATION OF IMMUNITY INDUCED BY INACTIVE VIRUS
title_full STUDIES IN HUMAN IMMUNIZATION AGAINST INFLUENZA : DURATION OF IMMUNITY INDUCED BY INACTIVE VIRUS
title_fullStr STUDIES IN HUMAN IMMUNIZATION AGAINST INFLUENZA : DURATION OF IMMUNITY INDUCED BY INACTIVE VIRUS
title_full_unstemmed STUDIES IN HUMAN IMMUNIZATION AGAINST INFLUENZA : DURATION OF IMMUNITY INDUCED BY INACTIVE VIRUS
title_short STUDIES IN HUMAN IMMUNIZATION AGAINST INFLUENZA : DURATION OF IMMUNITY INDUCED BY INACTIVE VIRUS
title_sort studies in human immunization against influenza : duration of immunity induced by inactive virus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135471/
https://www.ncbi.nlm.nih.gov/pubmed/19871414
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