Cargando…

STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER)

1. Volunteers have been immunized with the purified specific antigen of Type V Shigella paradysenteriae (Flexner). The subjects developed a high titer of bacterial agglutinins and mouse-protective antibodies. The agglutinin titer fell moderately after a period of 6 months. The subjects responded fai...

Descripción completa

Detalles Bibliográficos
Autores principales: Perlman, Ely, Binkley, Francis, Goebel, Walther F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1945
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135497/
https://www.ncbi.nlm.nih.gov/pubmed/19871462
_version_ 1782142910868750336
author Perlman, Ely
Binkley, Francis
Goebel, Walther F.
author_facet Perlman, Ely
Binkley, Francis
Goebel, Walther F.
author_sort Perlman, Ely
collection PubMed
description 1. Volunteers have been immunized with the purified specific antigen of Type V Shigella paradysenteriae (Flexner). The subjects developed a high titer of bacterial agglutinins and mouse-protective antibodies. The agglutinin titer fell moderately after a period of 6 months. The subjects responded fairly well to a small recall dose of the antigen. 2. Two individuals from a group of 10 injected with the specific polysaccharide obtained from Type V organisms responded with an increase in bacterial agglutinins. Mouse-protective antibodies were demonstrable in the one serum tested.
format Text
id pubmed-2135497
institution National Center for Biotechnology Information
language English
publishDate 1945
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21354972008-04-18 STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER) Perlman, Ely Binkley, Francis Goebel, Walther F. J Exp Med Article 1. Volunteers have been immunized with the purified specific antigen of Type V Shigella paradysenteriae (Flexner). The subjects developed a high titer of bacterial agglutinins and mouse-protective antibodies. The agglutinin titer fell moderately after a period of 6 months. The subjects responded fairly well to a small recall dose of the antigen. 2. Two individuals from a group of 10 injected with the specific polysaccharide obtained from Type V organisms responded with an increase in bacterial agglutinins. Mouse-protective antibodies were demonstrable in the one serum tested. The Rockefeller University Press 1945-04-01 /pmc/articles/PMC2135497/ /pubmed/19871462 Text en Copyright © Copyright, 1945, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Perlman, Ely
Binkley, Francis
Goebel, Walther F.
STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER)
title STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER)
title_full STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER)
title_fullStr STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER)
title_full_unstemmed STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER)
title_short STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER)
title_sort studies on the flexner group of dysentery bacilli : iii. antibody response in man following the administration of the specific antigen of type v shigella paradysenteriae (flexner)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135497/
https://www.ncbi.nlm.nih.gov/pubmed/19871462
work_keys_str_mv AT perlmanely studiesontheflexnergroupofdysenterybacilliiiiantibodyresponseinmanfollowingtheadministrationofthespecificantigenoftypevshigellaparadysenteriaeflexner
AT binkleyfrancis studiesontheflexnergroupofdysenterybacilliiiiantibodyresponseinmanfollowingtheadministrationofthespecificantigenoftypevshigellaparadysenteriaeflexner
AT goebelwaltherf studiesontheflexnergroupofdysenterybacilliiiiantibodyresponseinmanfollowingtheadministrationofthespecificantigenoftypevshigellaparadysenteriaeflexner