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STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER)
1. Volunteers have been immunized with the purified specific antigen of Type V Shigella paradysenteriae (Flexner). The subjects developed a high titer of bacterial agglutinins and mouse-protective antibodies. The agglutinin titer fell moderately after a period of 6 months. The subjects responded fai...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1945
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135497/ https://www.ncbi.nlm.nih.gov/pubmed/19871462 |
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author | Perlman, Ely Binkley, Francis Goebel, Walther F. |
author_facet | Perlman, Ely Binkley, Francis Goebel, Walther F. |
author_sort | Perlman, Ely |
collection | PubMed |
description | 1. Volunteers have been immunized with the purified specific antigen of Type V Shigella paradysenteriae (Flexner). The subjects developed a high titer of bacterial agglutinins and mouse-protective antibodies. The agglutinin titer fell moderately after a period of 6 months. The subjects responded fairly well to a small recall dose of the antigen. 2. Two individuals from a group of 10 injected with the specific polysaccharide obtained from Type V organisms responded with an increase in bacterial agglutinins. Mouse-protective antibodies were demonstrable in the one serum tested. |
format | Text |
id | pubmed-2135497 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1945 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21354972008-04-18 STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER) Perlman, Ely Binkley, Francis Goebel, Walther F. J Exp Med Article 1. Volunteers have been immunized with the purified specific antigen of Type V Shigella paradysenteriae (Flexner). The subjects developed a high titer of bacterial agglutinins and mouse-protective antibodies. The agglutinin titer fell moderately after a period of 6 months. The subjects responded fairly well to a small recall dose of the antigen. 2. Two individuals from a group of 10 injected with the specific polysaccharide obtained from Type V organisms responded with an increase in bacterial agglutinins. Mouse-protective antibodies were demonstrable in the one serum tested. The Rockefeller University Press 1945-04-01 /pmc/articles/PMC2135497/ /pubmed/19871462 Text en Copyright © Copyright, 1945, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Perlman, Ely Binkley, Francis Goebel, Walther F. STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER) |
title | STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER) |
title_full | STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER) |
title_fullStr | STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER) |
title_full_unstemmed | STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER) |
title_short | STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : III. ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER) |
title_sort | studies on the flexner group of dysentery bacilli : iii. antibody response in man following the administration of the specific antigen of type v shigella paradysenteriae (flexner) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135497/ https://www.ncbi.nlm.nih.gov/pubmed/19871462 |
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