STUDIES ON MENINGOCOCCAL INFECTION : XIII. CORRELATION BETWEEN ANTIPOLYSACCHARIDE AND THE ANTIBODY WHICH PROTECTS MICE AGAINST INFECTION WITH TYPE I MENINGOCOCCI

Absorption tests indicated that the protective antibody (Type I) in four antimeningococcal horse sera corresponded closely to one of the components of the polysaccharide preparation previously isolated by the authors from Type I meningococci. This antibody was, however, a minor fraction in the three...

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Detalles Bibliográficos
Autores principales: Scherp, Henry W., Rake, Geoffrey
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1945
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135524/
https://www.ncbi.nlm.nih.gov/pubmed/19871446
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author Scherp, Henry W.
Rake, Geoffrey
author_facet Scherp, Henry W.
Rake, Geoffrey
author_sort Scherp, Henry W.
collection PubMed
description Absorption tests indicated that the protective antibody (Type I) in four antimeningococcal horse sera corresponded closely to one of the components of the polysaccharide preparation previously isolated by the authors from Type I meningococci. This antibody was, however, a minor fraction in the three therapeutic sera tested, being secondary in amount to non-protective antibody corresponding to another component of the polysaccharide preparation, plus antibody corresponding to agar. In one case, removal of the agar-antibody diminished the protective titer by 30 per cent.
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spelling pubmed-21355242008-04-18 STUDIES ON MENINGOCOCCAL INFECTION : XIII. CORRELATION BETWEEN ANTIPOLYSACCHARIDE AND THE ANTIBODY WHICH PROTECTS MICE AGAINST INFECTION WITH TYPE I MENINGOCOCCI Scherp, Henry W. Rake, Geoffrey J Exp Med Article Absorption tests indicated that the protective antibody (Type I) in four antimeningococcal horse sera corresponded closely to one of the components of the polysaccharide preparation previously isolated by the authors from Type I meningococci. This antibody was, however, a minor fraction in the three therapeutic sera tested, being secondary in amount to non-protective antibody corresponding to another component of the polysaccharide preparation, plus antibody corresponding to agar. In one case, removal of the agar-antibody diminished the protective titer by 30 per cent. The Rockefeller University Press 1945-01-01 /pmc/articles/PMC2135524/ /pubmed/19871446 Text en Copyright © Copyright, 1945, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Scherp, Henry W.
Rake, Geoffrey
STUDIES ON MENINGOCOCCAL INFECTION : XIII. CORRELATION BETWEEN ANTIPOLYSACCHARIDE AND THE ANTIBODY WHICH PROTECTS MICE AGAINST INFECTION WITH TYPE I MENINGOCOCCI
title STUDIES ON MENINGOCOCCAL INFECTION : XIII. CORRELATION BETWEEN ANTIPOLYSACCHARIDE AND THE ANTIBODY WHICH PROTECTS MICE AGAINST INFECTION WITH TYPE I MENINGOCOCCI
title_full STUDIES ON MENINGOCOCCAL INFECTION : XIII. CORRELATION BETWEEN ANTIPOLYSACCHARIDE AND THE ANTIBODY WHICH PROTECTS MICE AGAINST INFECTION WITH TYPE I MENINGOCOCCI
title_fullStr STUDIES ON MENINGOCOCCAL INFECTION : XIII. CORRELATION BETWEEN ANTIPOLYSACCHARIDE AND THE ANTIBODY WHICH PROTECTS MICE AGAINST INFECTION WITH TYPE I MENINGOCOCCI
title_full_unstemmed STUDIES ON MENINGOCOCCAL INFECTION : XIII. CORRELATION BETWEEN ANTIPOLYSACCHARIDE AND THE ANTIBODY WHICH PROTECTS MICE AGAINST INFECTION WITH TYPE I MENINGOCOCCI
title_short STUDIES ON MENINGOCOCCAL INFECTION : XIII. CORRELATION BETWEEN ANTIPOLYSACCHARIDE AND THE ANTIBODY WHICH PROTECTS MICE AGAINST INFECTION WITH TYPE I MENINGOCOCCI
title_sort studies on meningococcal infection : xiii. correlation between antipolysaccharide and the antibody which protects mice against infection with type i meningococci
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135524/
https://www.ncbi.nlm.nih.gov/pubmed/19871446
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