STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : II. EFFECT OF DESOXYRIBONUCLEASE ON THE BIOLOGICAL ACTIVITY OF THE TRANSFORMING SUBSTANCE

It has been shown that extremely minute amounts of purified preparations of desoxyribonuclease are capable of bringing about the complete and irreversible inactivation of the transforming substance of Pneumococcus Type III. The significance of the effect of the enzyme, and its bearing on the chemica...

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Detalles Bibliográficos
Autores principales: McCarty, Maclyn, Avery, Oswald T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1946
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135575/
https://www.ncbi.nlm.nih.gov/pubmed/19871520
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author McCarty, Maclyn
Avery, Oswald T.
author_facet McCarty, Maclyn
Avery, Oswald T.
author_sort McCarty, Maclyn
collection PubMed
description It has been shown that extremely minute amounts of purified preparations of desoxyribonuclease are capable of bringing about the complete and irreversible inactivation of the transforming substance of Pneumococcus Type III. The significance of the effect of the enzyme, and its bearing on the chemical nature of the transforming substance, together with certain considerations concerning the biological specificity of desoxyribonucleic acids in general, are discussed.
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spelling pubmed-21355752008-04-18 STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : II. EFFECT OF DESOXYRIBONUCLEASE ON THE BIOLOGICAL ACTIVITY OF THE TRANSFORMING SUBSTANCE McCarty, Maclyn Avery, Oswald T. J Exp Med Article It has been shown that extremely minute amounts of purified preparations of desoxyribonuclease are capable of bringing about the complete and irreversible inactivation of the transforming substance of Pneumococcus Type III. The significance of the effect of the enzyme, and its bearing on the chemical nature of the transforming substance, together with certain considerations concerning the biological specificity of desoxyribonucleic acids in general, are discussed. The Rockefeller University Press 1946-01-31 /pmc/articles/PMC2135575/ /pubmed/19871520 Text en Copyright © Copyright, 1946, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
McCarty, Maclyn
Avery, Oswald T.
STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : II. EFFECT OF DESOXYRIBONUCLEASE ON THE BIOLOGICAL ACTIVITY OF THE TRANSFORMING SUBSTANCE
title STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : II. EFFECT OF DESOXYRIBONUCLEASE ON THE BIOLOGICAL ACTIVITY OF THE TRANSFORMING SUBSTANCE
title_full STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : II. EFFECT OF DESOXYRIBONUCLEASE ON THE BIOLOGICAL ACTIVITY OF THE TRANSFORMING SUBSTANCE
title_fullStr STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : II. EFFECT OF DESOXYRIBONUCLEASE ON THE BIOLOGICAL ACTIVITY OF THE TRANSFORMING SUBSTANCE
title_full_unstemmed STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : II. EFFECT OF DESOXYRIBONUCLEASE ON THE BIOLOGICAL ACTIVITY OF THE TRANSFORMING SUBSTANCE
title_short STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : II. EFFECT OF DESOXYRIBONUCLEASE ON THE BIOLOGICAL ACTIVITY OF THE TRANSFORMING SUBSTANCE
title_sort studies on the chemical nature of the substance inducing transformation of pneumococcal types : ii. effect of desoxyribonuclease on the biological activity of the transforming substance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135575/
https://www.ncbi.nlm.nih.gov/pubmed/19871520
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AT averyoswaldt studiesonthechemicalnatureofthesubstanceinducingtransformationofpneumococcaltypesiieffectofdesoxyribonucleaseonthebiologicalactivityofthetransformingsubstance

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