SUPPRESSION OF GROWTH OF BROWN-PEARCE TUMOR CELLS BY A SPECIFIC ANTIBODY : WITH A CONSIDERATION OF THE NATURE OF THE REACTING CELL CONSTITUENT

Experiments are reported in detail which show that an antibody which appears in the blood of certain rabbits implanted with the Brown-Pearce tumor or injected with cell-free extracts of it is capable of suppressing the growth of the tumor cells under a variety of experimental conditions, the effects...

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Detalles Bibliográficos
Autor principal: Kidd, John G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1946
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135580/
https://www.ncbi.nlm.nih.gov/pubmed/19871527
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author Kidd, John G.
author_facet Kidd, John G.
author_sort Kidd, John G.
collection PubMed
description Experiments are reported in detail which show that an antibody which appears in the blood of certain rabbits implanted with the Brown-Pearce tumor or injected with cell-free extracts of it is capable of suppressing the growth of the tumor cells under a variety of experimental conditions, the effects of the antibody being wholly distinct from those of unknown factors that frequently bring about regression of the growth. The implications of the findings are discussed with particular reference to facts indicating that the distinctive cell constituent with which the antibody reacts may play a significant part in the proliferative activities of the Brown-Pearce tumor cell.
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spelling pubmed-21355802008-04-18 SUPPRESSION OF GROWTH OF BROWN-PEARCE TUMOR CELLS BY A SPECIFIC ANTIBODY : WITH A CONSIDERATION OF THE NATURE OF THE REACTING CELL CONSTITUENT Kidd, John G. J Exp Med Article Experiments are reported in detail which show that an antibody which appears in the blood of certain rabbits implanted with the Brown-Pearce tumor or injected with cell-free extracts of it is capable of suppressing the growth of the tumor cells under a variety of experimental conditions, the effects of the antibody being wholly distinct from those of unknown factors that frequently bring about regression of the growth. The implications of the findings are discussed with particular reference to facts indicating that the distinctive cell constituent with which the antibody reacts may play a significant part in the proliferative activities of the Brown-Pearce tumor cell. The Rockefeller University Press 1946-02-28 /pmc/articles/PMC2135580/ /pubmed/19871527 Text en Copyright © Copyright, 1946, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Kidd, John G.
SUPPRESSION OF GROWTH OF BROWN-PEARCE TUMOR CELLS BY A SPECIFIC ANTIBODY : WITH A CONSIDERATION OF THE NATURE OF THE REACTING CELL CONSTITUENT
title SUPPRESSION OF GROWTH OF BROWN-PEARCE TUMOR CELLS BY A SPECIFIC ANTIBODY : WITH A CONSIDERATION OF THE NATURE OF THE REACTING CELL CONSTITUENT
title_full SUPPRESSION OF GROWTH OF BROWN-PEARCE TUMOR CELLS BY A SPECIFIC ANTIBODY : WITH A CONSIDERATION OF THE NATURE OF THE REACTING CELL CONSTITUENT
title_fullStr SUPPRESSION OF GROWTH OF BROWN-PEARCE TUMOR CELLS BY A SPECIFIC ANTIBODY : WITH A CONSIDERATION OF THE NATURE OF THE REACTING CELL CONSTITUENT
title_full_unstemmed SUPPRESSION OF GROWTH OF BROWN-PEARCE TUMOR CELLS BY A SPECIFIC ANTIBODY : WITH A CONSIDERATION OF THE NATURE OF THE REACTING CELL CONSTITUENT
title_short SUPPRESSION OF GROWTH OF BROWN-PEARCE TUMOR CELLS BY A SPECIFIC ANTIBODY : WITH A CONSIDERATION OF THE NATURE OF THE REACTING CELL CONSTITUENT
title_sort suppression of growth of brown-pearce tumor cells by a specific antibody : with a consideration of the nature of the reacting cell constituent
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135580/
https://www.ncbi.nlm.nih.gov/pubmed/19871527
work_keys_str_mv AT kiddjohng suppressionofgrowthofbrownpearcetumorcellsbyaspecificantibodywithaconsiderationofthenatureofthereactingcellconstituent

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