FACTORS AFFECTING THE GROWTH OF TUBERCLE BACILLI IN LIQUID MEDIA

1. Certain water-soluble esters of long chain fatty acids (in particular of oleic acid) favor submerged and diffuse growth of mycobacteria throughout the depth of synthetic liquid media. 2. Esters of oleic acid increase considerably the amount of growth yielded by avian strains in synthetic media. 3...

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Detalles Bibliográficos
Autores principales: Dubos, René J., Davis, Bernard D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1946
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135599/
https://www.ncbi.nlm.nih.gov/pubmed/19871539
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author Dubos, René J.
Davis, Bernard D.
author_facet Dubos, René J.
Davis, Bernard D.
author_sort Dubos, René J.
collection PubMed
description 1. Certain water-soluble esters of long chain fatty acids (in particular of oleic acid) favor submerged and diffuse growth of mycobacteria throughout the depth of synthetic liquid media. 2. Esters of oleic acid increase considerably the amount of growth yielded by avian strains in synthetic media. 3. The addition of serum albumin to synthetic liquid media permits visible growth of minimal inocula of virulent human tubercle bacilli (10(–8) mg.) within 11 to 15 days. 4. Cultures growing diffusely in media containing the water-soluble esters— with or without albumin—consist of cells of classical morphology and staining properties, which again exhibit the usual mode of growth when returned to the standard synthetic or egg yolk media.
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spelling pubmed-21355992008-04-18 FACTORS AFFECTING THE GROWTH OF TUBERCLE BACILLI IN LIQUID MEDIA Dubos, René J. Davis, Bernard D. J Exp Med Article 1. Certain water-soluble esters of long chain fatty acids (in particular of oleic acid) favor submerged and diffuse growth of mycobacteria throughout the depth of synthetic liquid media. 2. Esters of oleic acid increase considerably the amount of growth yielded by avian strains in synthetic media. 3. The addition of serum albumin to synthetic liquid media permits visible growth of minimal inocula of virulent human tubercle bacilli (10(–8) mg.) within 11 to 15 days. 4. Cultures growing diffusely in media containing the water-soluble esters— with or without albumin—consist of cells of classical morphology and staining properties, which again exhibit the usual mode of growth when returned to the standard synthetic or egg yolk media. The Rockefeller University Press 1946-04-30 /pmc/articles/PMC2135599/ /pubmed/19871539 Text en Copyright © Copyright, 1946, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Dubos, René J.
Davis, Bernard D.
FACTORS AFFECTING THE GROWTH OF TUBERCLE BACILLI IN LIQUID MEDIA
title FACTORS AFFECTING THE GROWTH OF TUBERCLE BACILLI IN LIQUID MEDIA
title_full FACTORS AFFECTING THE GROWTH OF TUBERCLE BACILLI IN LIQUID MEDIA
title_fullStr FACTORS AFFECTING THE GROWTH OF TUBERCLE BACILLI IN LIQUID MEDIA
title_full_unstemmed FACTORS AFFECTING THE GROWTH OF TUBERCLE BACILLI IN LIQUID MEDIA
title_short FACTORS AFFECTING THE GROWTH OF TUBERCLE BACILLI IN LIQUID MEDIA
title_sort factors affecting the growth of tubercle bacilli in liquid media
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135599/
https://www.ncbi.nlm.nih.gov/pubmed/19871539
work_keys_str_mv AT dubosrenej factorsaffectingthegrowthoftuberclebacilliinliquidmedia
AT davisbernardd factorsaffectingthegrowthoftuberclebacilliinliquidmedia

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