PROPERTIES OF PNEUMONIA VIRUS OF MICE (PVM) IN RELATION TO ITS STATE

Additional evidence is presented that PVM is capable of combining firmly with lung tissue particles or erythrocytes from certain susceptible species. Release of the virus from such combination can be effected by treatment with alkali as well as by heating. Free virus expressed from infected lungs wi...

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Detalles Bibliográficos
Autores principales: Curnen, Edward C., Horsfall, Frank L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1947
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135673/
https://www.ncbi.nlm.nih.gov/pubmed/19871598
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author Curnen, Edward C.
Horsfall, Frank L.
author_facet Curnen, Edward C.
Horsfall, Frank L.
author_sort Curnen, Edward C.
collection PubMed
description Additional evidence is presented that PVM is capable of combining firmly with lung tissue particles or erythrocytes from certain susceptible species. Release of the virus from such combination can be effected by treatment with alkali as well as by heating. Free virus expressed from infected lungs without grinding the tissues is infectious and causes hemagglutination when tested directly. The concentration of virus can be estimated more accurately by means of the hemagglutination technique than from the results of infectivity tests in mice. Present evidence indicates that PVM may occur in 4 different states and that in each state it manifests distinctive properties.
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spelling pubmed-21356732008-04-18 PROPERTIES OF PNEUMONIA VIRUS OF MICE (PVM) IN RELATION TO ITS STATE Curnen, Edward C. Horsfall, Frank L. J Exp Med Article Additional evidence is presented that PVM is capable of combining firmly with lung tissue particles or erythrocytes from certain susceptible species. Release of the virus from such combination can be effected by treatment with alkali as well as by heating. Free virus expressed from infected lungs without grinding the tissues is infectious and causes hemagglutination when tested directly. The concentration of virus can be estimated more accurately by means of the hemagglutination technique than from the results of infectivity tests in mice. Present evidence indicates that PVM may occur in 4 different states and that in each state it manifests distinctive properties. The Rockefeller University Press 1947-01-01 /pmc/articles/PMC2135673/ /pubmed/19871598 Text en Copyright © Copyright, 1947, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Curnen, Edward C.
Horsfall, Frank L.
PROPERTIES OF PNEUMONIA VIRUS OF MICE (PVM) IN RELATION TO ITS STATE
title PROPERTIES OF PNEUMONIA VIRUS OF MICE (PVM) IN RELATION TO ITS STATE
title_full PROPERTIES OF PNEUMONIA VIRUS OF MICE (PVM) IN RELATION TO ITS STATE
title_fullStr PROPERTIES OF PNEUMONIA VIRUS OF MICE (PVM) IN RELATION TO ITS STATE
title_full_unstemmed PROPERTIES OF PNEUMONIA VIRUS OF MICE (PVM) IN RELATION TO ITS STATE
title_short PROPERTIES OF PNEUMONIA VIRUS OF MICE (PVM) IN RELATION TO ITS STATE
title_sort properties of pneumonia virus of mice (pvm) in relation to its state
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135673/
https://www.ncbi.nlm.nih.gov/pubmed/19871598
work_keys_str_mv AT curnenedwardc propertiesofpneumoniavirusofmicepvminrelationtoitsstate
AT horsfallfrankl propertiesofpneumoniavirusofmicepvminrelationtoitsstate

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