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STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : VI. THE DETOXIFICATION OF SHIGELLA PARADYSENTERIAE BY MEANS OF PERIODIC ACID
A method for detoxifying Type Z and sp. Newcastle Sh. paradysenteriae (Flexner) has been described. This procedure involves exposing the bacilli at pH 5.0 to 0.01 M periodic acid. Microorganisms treated with this reagent for an appropriate time interval lose approximately 90 per cent of their toxici...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1947
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135711/ https://www.ncbi.nlm.nih.gov/pubmed/19871632 |
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author | Goebel, Walther F. |
author_facet | Goebel, Walther F. |
author_sort | Goebel, Walther F. |
collection | PubMed |
description | A method for detoxifying Type Z and sp. Newcastle Sh. paradysenteriae (Flexner) has been described. This procedure involves exposing the bacilli at pH 5.0 to 0.01 M periodic acid. Microorganisms treated with this reagent for an appropriate time interval lose approximately 90 per cent of their toxicity, yet they are capable of eliciting in experimental animals antibodies effective against the unaltered organisms. |
format | Text |
id | pubmed-2135711 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1947 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21357112008-04-18 STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : VI. THE DETOXIFICATION OF SHIGELLA PARADYSENTERIAE BY MEANS OF PERIODIC ACID Goebel, Walther F. J Exp Med Article A method for detoxifying Type Z and sp. Newcastle Sh. paradysenteriae (Flexner) has been described. This procedure involves exposing the bacilli at pH 5.0 to 0.01 M periodic acid. Microorganisms treated with this reagent for an appropriate time interval lose approximately 90 per cent of their toxicity, yet they are capable of eliciting in experimental animals antibodies effective against the unaltered organisms. The Rockefeller University Press 1947-04-30 /pmc/articles/PMC2135711/ /pubmed/19871632 Text en Copyright © Copyright, 1947, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Goebel, Walther F. STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : VI. THE DETOXIFICATION OF SHIGELLA PARADYSENTERIAE BY MEANS OF PERIODIC ACID |
title | STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : VI. THE DETOXIFICATION OF SHIGELLA PARADYSENTERIAE BY MEANS OF PERIODIC ACID |
title_full | STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : VI. THE DETOXIFICATION OF SHIGELLA PARADYSENTERIAE BY MEANS OF PERIODIC ACID |
title_fullStr | STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : VI. THE DETOXIFICATION OF SHIGELLA PARADYSENTERIAE BY MEANS OF PERIODIC ACID |
title_full_unstemmed | STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : VI. THE DETOXIFICATION OF SHIGELLA PARADYSENTERIAE BY MEANS OF PERIODIC ACID |
title_short | STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : VI. THE DETOXIFICATION OF SHIGELLA PARADYSENTERIAE BY MEANS OF PERIODIC ACID |
title_sort | studies on the flexner group of dysentery bacilli : vi. the detoxification of shigella paradysenteriae by means of periodic acid |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135711/ https://www.ncbi.nlm.nih.gov/pubmed/19871632 |
work_keys_str_mv | AT goebelwaltherf studiesontheflexnergroupofdysenterybacillivithedetoxificationofshigellaparadysenteriaebymeansofperiodicacid |