ANTIPROTEINS IN HORSE SERA : III. ANTIBODIES TO RABBIT SERUM ALBUMIN AND THEIR REACTION WITH ANTIGEN

1. Two horses were injected subcutaneously with alum-precipitated rabbit serum albumin. 2. The resulting antibody resembled diphtheria antitoxin and anti-egg albumin in the horse in giving a sharp zone of flocculation with antigen, in being water-soluble, in reactivity toward an anti-antibody rabbit...

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Autores principales: Treffers, Henry P., Heidelberger, Michael, Freund, Jules
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1947
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135715/
https://www.ncbi.nlm.nih.gov/pubmed/19871668
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author Treffers, Henry P.
Heidelberger, Michael
Freund, Jules
author_facet Treffers, Henry P.
Heidelberger, Michael
Freund, Jules
author_sort Treffers, Henry P.
collection PubMed
description 1. Two horses were injected subcutaneously with alum-precipitated rabbit serum albumin. 2. The resulting antibody resembled diphtheria antitoxin and anti-egg albumin in the horse in giving a sharp zone of flocculation with antigen, in being water-soluble, in reactivity toward an anti-antibody rabbit serum, and in its electrophoretic properties. 3. The effect of continued immunization, and of variation in volume and temperature on the reactivity of the antibody are discussed. 4. Intravenous injection of the same antigen into horses did not give rise to detectable amounts of antibody of the same type.
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spelling pubmed-21357152008-04-18 ANTIPROTEINS IN HORSE SERA : III. ANTIBODIES TO RABBIT SERUM ALBUMIN AND THEIR REACTION WITH ANTIGEN Treffers, Henry P. Heidelberger, Michael Freund, Jules J Exp Med Article 1. Two horses were injected subcutaneously with alum-precipitated rabbit serum albumin. 2. The resulting antibody resembled diphtheria antitoxin and anti-egg albumin in the horse in giving a sharp zone of flocculation with antigen, in being water-soluble, in reactivity toward an anti-antibody rabbit serum, and in its electrophoretic properties. 3. The effect of continued immunization, and of variation in volume and temperature on the reactivity of the antibody are discussed. 4. Intravenous injection of the same antigen into horses did not give rise to detectable amounts of antibody of the same type. The Rockefeller University Press 1947-07-31 /pmc/articles/PMC2135715/ /pubmed/19871668 Text en Copyright © Copyright, 1947, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Treffers, Henry P.
Heidelberger, Michael
Freund, Jules
ANTIPROTEINS IN HORSE SERA : III. ANTIBODIES TO RABBIT SERUM ALBUMIN AND THEIR REACTION WITH ANTIGEN
title ANTIPROTEINS IN HORSE SERA : III. ANTIBODIES TO RABBIT SERUM ALBUMIN AND THEIR REACTION WITH ANTIGEN
title_full ANTIPROTEINS IN HORSE SERA : III. ANTIBODIES TO RABBIT SERUM ALBUMIN AND THEIR REACTION WITH ANTIGEN
title_fullStr ANTIPROTEINS IN HORSE SERA : III. ANTIBODIES TO RABBIT SERUM ALBUMIN AND THEIR REACTION WITH ANTIGEN
title_full_unstemmed ANTIPROTEINS IN HORSE SERA : III. ANTIBODIES TO RABBIT SERUM ALBUMIN AND THEIR REACTION WITH ANTIGEN
title_short ANTIPROTEINS IN HORSE SERA : III. ANTIBODIES TO RABBIT SERUM ALBUMIN AND THEIR REACTION WITH ANTIGEN
title_sort antiproteins in horse sera : iii. antibodies to rabbit serum albumin and their reaction with antigen
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135715/
https://www.ncbi.nlm.nih.gov/pubmed/19871668
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AT freundjules antiproteinsinhorseseraiiiantibodiestorabbitserumalbuminandtheirreactionwithantigen

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