RENAL ATHROCYTOSIS AND INTRACELLULAR DIGESTION OF INTRAPERITONEALLY INJECTED HEMOGLOBIN IN RATS

The athrocytosis of hemoglobin by the epithelium of the proximal convoluted tubules in the kidney of the rat was studied after its intraperitoneal injection, absorption into the blood stream, and glomerular filtration. The earliest appearance of the athrocytosed particles, their accumulation, intrac...

Descripción completa

Detalles Bibliográficos
Autor principal: Rather, L. J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1948
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135765/
https://www.ncbi.nlm.nih.gov/pubmed/18911177
_version_ 1782142971773190144
author Rather, L. J.
author_facet Rather, L. J.
author_sort Rather, L. J.
collection PubMed
description The athrocytosis of hemoglobin by the epithelium of the proximal convoluted tubules in the kidney of the rat was studied after its intraperitoneal injection, absorption into the blood stream, and glomerular filtration. The earliest appearance of the athrocytosed particles, their accumulation, intracellular breakdown, and disappearance were followed. In addition observations were made on the intraluminal disposition of hemoglobin "casts" with the Spalteholz clearing technique; on the structural changes in the kidney in consequence of the injections; and on the development of a transient oliguria during the course of the experiment. The significance of the findings is considered.
format Text
id pubmed-2135765
institution National Center for Biotechnology Information
language English
publishDate 1948
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21357652008-04-18 RENAL ATHROCYTOSIS AND INTRACELLULAR DIGESTION OF INTRAPERITONEALLY INJECTED HEMOGLOBIN IN RATS Rather, L. J. J Exp Med Article The athrocytosis of hemoglobin by the epithelium of the proximal convoluted tubules in the kidney of the rat was studied after its intraperitoneal injection, absorption into the blood stream, and glomerular filtration. The earliest appearance of the athrocytosed particles, their accumulation, intracellular breakdown, and disappearance were followed. In addition observations were made on the intraluminal disposition of hemoglobin "casts" with the Spalteholz clearing technique; on the structural changes in the kidney in consequence of the injections; and on the development of a transient oliguria during the course of the experiment. The significance of the findings is considered. The Rockefeller University Press 1948-01-31 /pmc/articles/PMC2135765/ /pubmed/18911177 Text en Copyright © Copyright, 1948, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Rather, L. J.
RENAL ATHROCYTOSIS AND INTRACELLULAR DIGESTION OF INTRAPERITONEALLY INJECTED HEMOGLOBIN IN RATS
title RENAL ATHROCYTOSIS AND INTRACELLULAR DIGESTION OF INTRAPERITONEALLY INJECTED HEMOGLOBIN IN RATS
title_full RENAL ATHROCYTOSIS AND INTRACELLULAR DIGESTION OF INTRAPERITONEALLY INJECTED HEMOGLOBIN IN RATS
title_fullStr RENAL ATHROCYTOSIS AND INTRACELLULAR DIGESTION OF INTRAPERITONEALLY INJECTED HEMOGLOBIN IN RATS
title_full_unstemmed RENAL ATHROCYTOSIS AND INTRACELLULAR DIGESTION OF INTRAPERITONEALLY INJECTED HEMOGLOBIN IN RATS
title_short RENAL ATHROCYTOSIS AND INTRACELLULAR DIGESTION OF INTRAPERITONEALLY INJECTED HEMOGLOBIN IN RATS
title_sort renal athrocytosis and intracellular digestion of intraperitoneally injected hemoglobin in rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135765/
https://www.ncbi.nlm.nih.gov/pubmed/18911177
work_keys_str_mv AT ratherlj renalathrocytosisandintracellulardigestionofintraperitoneallyinjectedhemoglobininrats

Ejemplares similares