THE INFLUENCE OF AVAILABLE FLUID ON THE PRODUCTION OF EXPERIMENTAL HEMOGLOBINURIC NEPHROSIS IN RABBITS

The importance of previous dehydration on the production of hemoglobinuric nephrosis is substantiated. Hemoglobinuric nephrosis regularly occurred in rabbits 3 to 16 days following the injections of hemoglobin. Five of 15 animals died of fatal hemoglobinuric nephrosis; the combined kidney weight in...

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Detalles Bibliográficos
Autor principal: Lalich, Joseph J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1948
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135768/
https://www.ncbi.nlm.nih.gov/pubmed/18911176
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author Lalich, Joseph J.
author_facet Lalich, Joseph J.
author_sort Lalich, Joseph J.
collection PubMed
description The importance of previous dehydration on the production of hemoglobinuric nephrosis is substantiated. Hemoglobinuric nephrosis regularly occurred in rabbits 3 to 16 days following the injections of hemoglobin. Five of 15 animals died of fatal hemoglobinuric nephrosis; the combined kidney weight in these exceeded the weight of the kidneys of control rabbits and of those which survived. Additional observations, not previously made, are focal necrosis of the liver and pulmonary edema in some of the rabbits which died. A relationship was evident between the quantity of available fluid and the severity of the hemoglobinuric nephrosis which developed after injections of hemoglobin.
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spelling pubmed-21357682008-04-18 THE INFLUENCE OF AVAILABLE FLUID ON THE PRODUCTION OF EXPERIMENTAL HEMOGLOBINURIC NEPHROSIS IN RABBITS Lalich, Joseph J. J Exp Med Article The importance of previous dehydration on the production of hemoglobinuric nephrosis is substantiated. Hemoglobinuric nephrosis regularly occurred in rabbits 3 to 16 days following the injections of hemoglobin. Five of 15 animals died of fatal hemoglobinuric nephrosis; the combined kidney weight in these exceeded the weight of the kidneys of control rabbits and of those which survived. Additional observations, not previously made, are focal necrosis of the liver and pulmonary edema in some of the rabbits which died. A relationship was evident between the quantity of available fluid and the severity of the hemoglobinuric nephrosis which developed after injections of hemoglobin. The Rockefeller University Press 1948-01-31 /pmc/articles/PMC2135768/ /pubmed/18911176 Text en Copyright © Copyright, 1948, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Lalich, Joseph J.
THE INFLUENCE OF AVAILABLE FLUID ON THE PRODUCTION OF EXPERIMENTAL HEMOGLOBINURIC NEPHROSIS IN RABBITS
title THE INFLUENCE OF AVAILABLE FLUID ON THE PRODUCTION OF EXPERIMENTAL HEMOGLOBINURIC NEPHROSIS IN RABBITS
title_full THE INFLUENCE OF AVAILABLE FLUID ON THE PRODUCTION OF EXPERIMENTAL HEMOGLOBINURIC NEPHROSIS IN RABBITS
title_fullStr THE INFLUENCE OF AVAILABLE FLUID ON THE PRODUCTION OF EXPERIMENTAL HEMOGLOBINURIC NEPHROSIS IN RABBITS
title_full_unstemmed THE INFLUENCE OF AVAILABLE FLUID ON THE PRODUCTION OF EXPERIMENTAL HEMOGLOBINURIC NEPHROSIS IN RABBITS
title_short THE INFLUENCE OF AVAILABLE FLUID ON THE PRODUCTION OF EXPERIMENTAL HEMOGLOBINURIC NEPHROSIS IN RABBITS
title_sort influence of available fluid on the production of experimental hemoglobinuric nephrosis in rabbits
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135768/
https://www.ncbi.nlm.nih.gov/pubmed/18911176
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