THE INACTIVATION OF BIOLOGICALLY ACTIVE PROTEINS, AND THE VIRUS OF WESTERN EQUINE ENCEPHALOMYELITIS BY PERIODIC ACID

The action of periodic acid on two biologically active proteins, crystalline ribonuclease and pneumococcus Type III immune globulin, and on the virus of Western equine encephalomyelitis has been studied. The biological activity of the two proteins and the pathogenic action of the virus were destroye...

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Detalles Bibliográficos
Autores principales: Goebel, Walther F., Olitsky, Peter K., Saenz, Arturo C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1948
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135787/
https://www.ncbi.nlm.nih.gov/pubmed/18912894
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author Goebel, Walther F.
Olitsky, Peter K.
Saenz, Arturo C.
author_facet Goebel, Walther F.
Olitsky, Peter K.
Saenz, Arturo C.
author_sort Goebel, Walther F.
collection PubMed
description The action of periodic acid on two biologically active proteins, crystalline ribonuclease and pneumococcus Type III immune globulin, and on the virus of Western equine encephalomyelitis has been studied. The biological activity of the two proteins and the pathogenic action of the virus were destroyed by the reagent; the specific antigenicity of the immune globulin was retained, however, but that of the equine virus was lost. The bearing of these reactions on the chemical alteration of the respective substances has been discussed.
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spelling pubmed-21357872008-04-18 THE INACTIVATION OF BIOLOGICALLY ACTIVE PROTEINS, AND THE VIRUS OF WESTERN EQUINE ENCEPHALOMYELITIS BY PERIODIC ACID Goebel, Walther F. Olitsky, Peter K. Saenz, Arturo C. J Exp Med Article The action of periodic acid on two biologically active proteins, crystalline ribonuclease and pneumococcus Type III immune globulin, and on the virus of Western equine encephalomyelitis has been studied. The biological activity of the two proteins and the pathogenic action of the virus were destroyed by the reagent; the specific antigenicity of the immune globulin was retained, however, but that of the equine virus was lost. The bearing of these reactions on the chemical alteration of the respective substances has been discussed. The Rockefeller University Press 1948-05-01 /pmc/articles/PMC2135787/ /pubmed/18912894 Text en Copyright © Copyright, 1948, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Goebel, Walther F.
Olitsky, Peter K.
Saenz, Arturo C.
THE INACTIVATION OF BIOLOGICALLY ACTIVE PROTEINS, AND THE VIRUS OF WESTERN EQUINE ENCEPHALOMYELITIS BY PERIODIC ACID
title THE INACTIVATION OF BIOLOGICALLY ACTIVE PROTEINS, AND THE VIRUS OF WESTERN EQUINE ENCEPHALOMYELITIS BY PERIODIC ACID
title_full THE INACTIVATION OF BIOLOGICALLY ACTIVE PROTEINS, AND THE VIRUS OF WESTERN EQUINE ENCEPHALOMYELITIS BY PERIODIC ACID
title_fullStr THE INACTIVATION OF BIOLOGICALLY ACTIVE PROTEINS, AND THE VIRUS OF WESTERN EQUINE ENCEPHALOMYELITIS BY PERIODIC ACID
title_full_unstemmed THE INACTIVATION OF BIOLOGICALLY ACTIVE PROTEINS, AND THE VIRUS OF WESTERN EQUINE ENCEPHALOMYELITIS BY PERIODIC ACID
title_short THE INACTIVATION OF BIOLOGICALLY ACTIVE PROTEINS, AND THE VIRUS OF WESTERN EQUINE ENCEPHALOMYELITIS BY PERIODIC ACID
title_sort inactivation of biologically active proteins, and the virus of western equine encephalomyelitis by periodic acid
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135787/
https://www.ncbi.nlm.nih.gov/pubmed/18912894
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