STUDIES ON THE RELATIONSHIP OF PTEROYLGLUTAMIC ACID TO THE GROWTH OF PSITTACOSIS VIRUS (STRAIN 6BC)

p-Aminobenzoic and pteroic acids antagonize the inhibition of the growth of psittacosis virus (strain 6BC) by sulfadiazine in a competitive manner. Pteroylglutamic acid exerts a non-competitive type sulfonamide antagonism. The effects of certain analogues of pteroylglutamic acid and of pteroic acid...

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Detalles Bibliográficos
Autor principal: Morgan, Herbert R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1948
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135822/
https://www.ncbi.nlm.nih.gov/pubmed/18881487
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author Morgan, Herbert R.
author_facet Morgan, Herbert R.
author_sort Morgan, Herbert R.
collection PubMed
description p-Aminobenzoic and pteroic acids antagonize the inhibition of the growth of psittacosis virus (strain 6BC) by sulfadiazine in a competitive manner. Pteroylglutamic acid exerts a non-competitive type sulfonamide antagonism. The effects of certain analogues of pteroylglutamic acid and of pteroic acid on the growth of psittacosis virus and its inhibition by sulfadiazine are reported. The implications of these findings with regard to the possible synthesis of pteroylglutamic acid by psittacosis virus and its suggested rôle as an essential factor for growth of this virus are discussed.
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spelling pubmed-21358222008-04-18 STUDIES ON THE RELATIONSHIP OF PTEROYLGLUTAMIC ACID TO THE GROWTH OF PSITTACOSIS VIRUS (STRAIN 6BC) Morgan, Herbert R. J Exp Med Article p-Aminobenzoic and pteroic acids antagonize the inhibition of the growth of psittacosis virus (strain 6BC) by sulfadiazine in a competitive manner. Pteroylglutamic acid exerts a non-competitive type sulfonamide antagonism. The effects of certain analogues of pteroylglutamic acid and of pteroic acid on the growth of psittacosis virus and its inhibition by sulfadiazine are reported. The implications of these findings with regard to the possible synthesis of pteroylglutamic acid by psittacosis virus and its suggested rôle as an essential factor for growth of this virus are discussed. The Rockefeller University Press 1948-09-01 /pmc/articles/PMC2135822/ /pubmed/18881487 Text en Copyright © Copyright, 1948, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Morgan, Herbert R.
STUDIES ON THE RELATIONSHIP OF PTEROYLGLUTAMIC ACID TO THE GROWTH OF PSITTACOSIS VIRUS (STRAIN 6BC)
title STUDIES ON THE RELATIONSHIP OF PTEROYLGLUTAMIC ACID TO THE GROWTH OF PSITTACOSIS VIRUS (STRAIN 6BC)
title_full STUDIES ON THE RELATIONSHIP OF PTEROYLGLUTAMIC ACID TO THE GROWTH OF PSITTACOSIS VIRUS (STRAIN 6BC)
title_fullStr STUDIES ON THE RELATIONSHIP OF PTEROYLGLUTAMIC ACID TO THE GROWTH OF PSITTACOSIS VIRUS (STRAIN 6BC)
title_full_unstemmed STUDIES ON THE RELATIONSHIP OF PTEROYLGLUTAMIC ACID TO THE GROWTH OF PSITTACOSIS VIRUS (STRAIN 6BC)
title_short STUDIES ON THE RELATIONSHIP OF PTEROYLGLUTAMIC ACID TO THE GROWTH OF PSITTACOSIS VIRUS (STRAIN 6BC)
title_sort studies on the relationship of pteroylglutamic acid to the growth of psittacosis virus (strain 6bc)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135822/
https://www.ncbi.nlm.nih.gov/pubmed/18881487
work_keys_str_mv AT morganherbertr studiesontherelationshipofpteroylglutamicacidtothegrowthofpsittacosisvirusstrain6bc

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