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THE RELATION OF INFECTIOUS AND HEMAGGLUTINATION TITERS TO THE ADAPTATION OF INFLUENZA VIRUS TO MICE

The non-pathogenic (unadapted) line of the Rhodes strain of influenza virus multiplied readily in the mouse lung, but its rate of multiplication was slower and its hemagglutination titer attained at the peak of growth was much lower than that of the adapted line of the same virus. The implication of...

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Detalles Bibliográficos
Autor principal: Wang, Cheng-I
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1948
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135838/
https://www.ncbi.nlm.nih.gov/pubmed/18892426
Descripción
Sumario:The non-pathogenic (unadapted) line of the Rhodes strain of influenza virus multiplied readily in the mouse lung, but its rate of multiplication was slower and its hemagglutination titer attained at the peak of growth was much lower than that of the adapted line of the same virus. The implication of these findings to mouse adaptability of the virus is discussed.