THE SUSCEPTIBILITY OF THE HAMSTER TO MOUSE ENCEPHALOMYELITIS VIRUS

The OT strain of mouse encephalomyelitis virus induces an inapparent infection in suckling hamsters associated with lesions of the central nervous system and skeletal muscles. The virus increases in pathogenicity after alternating mouse-hamster transfers and then induces both paralysis and encephali...

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Detalles Bibliográficos
Autores principales: Dean, Donald J., Dalldorf, Gilbert
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1948
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135843/
https://www.ncbi.nlm.nih.gov/pubmed/18103400
Descripción
Sumario:The OT strain of mouse encephalomyelitis virus induces an inapparent infection in suckling hamsters associated with lesions of the central nervous system and skeletal muscles. The virus increases in pathogenicity after alternating mouse-hamster transfers and then induces both paralysis and encephalitis. Pathogenicity is lost through serial hamster passages but is restored by a single mouse transfer.

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