THE ASSOCIATIVE REACTIONS OF PNEUMONIA VIRUS OF MICE (PVM) AND INFLUENZA VIRUSES: THE EFFECTS OF pH AND ELECTROLYTES UPON VIRUS-HOST CELL COMBINATIONS

Combination between PVM and erythrocytes as well as between the influenza viruses and erythrocytes is inhibited at low electrolyte concentrations. Combination between PVM and lung particles as well as between the virus and erythrocytes can be dissociated in solutions of low electrolyte concentration...

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Detalles Bibliográficos
Autores principales: Davenport, Fred M., Horsfall, Frank L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1948
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135846/
https://www.ncbi.nlm.nih.gov/pubmed/18103399
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author Davenport, Fred M.
Horsfall, Frank L.
author_facet Davenport, Fred M.
Horsfall, Frank L.
author_sort Davenport, Fred M.
collection PubMed
description Combination between PVM and erythrocytes as well as between the influenza viruses and erythrocytes is inhibited at low electrolyte concentrations. Combination between PVM and lung particles as well as between the virus and erythrocytes can be dissociated in solutions of low electrolyte concentration. The rate of elution of influenza virus is decreased under similar conditions. PVM can combine with and be dissociated from erythrocytes repeatedly without affecting the combining capacity of the ceils and does not possess an enzyme-like activity similar to that of the influenza viruses. Because dissociation depends on electrolyte concentration and pH, it appears that the PVM-cell component complex may be in the nature of a weak salt.
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spelling pubmed-21358462008-04-18 THE ASSOCIATIVE REACTIONS OF PNEUMONIA VIRUS OF MICE (PVM) AND INFLUENZA VIRUSES: THE EFFECTS OF pH AND ELECTROLYTES UPON VIRUS-HOST CELL COMBINATIONS Davenport, Fred M. Horsfall, Frank L. J Exp Med Article Combination between PVM and erythrocytes as well as between the influenza viruses and erythrocytes is inhibited at low electrolyte concentrations. Combination between PVM and lung particles as well as between the virus and erythrocytes can be dissociated in solutions of low electrolyte concentration. The rate of elution of influenza virus is decreased under similar conditions. PVM can combine with and be dissociated from erythrocytes repeatedly without affecting the combining capacity of the ceils and does not possess an enzyme-like activity similar to that of the influenza viruses. Because dissociation depends on electrolyte concentration and pH, it appears that the PVM-cell component complex may be in the nature of a weak salt. The Rockefeller University Press 1948-12-01 /pmc/articles/PMC2135846/ /pubmed/18103399 Text en Copyright © Copyright, 1948, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Davenport, Fred M.
Horsfall, Frank L.
THE ASSOCIATIVE REACTIONS OF PNEUMONIA VIRUS OF MICE (PVM) AND INFLUENZA VIRUSES: THE EFFECTS OF pH AND ELECTROLYTES UPON VIRUS-HOST CELL COMBINATIONS
title THE ASSOCIATIVE REACTIONS OF PNEUMONIA VIRUS OF MICE (PVM) AND INFLUENZA VIRUSES: THE EFFECTS OF pH AND ELECTROLYTES UPON VIRUS-HOST CELL COMBINATIONS
title_full THE ASSOCIATIVE REACTIONS OF PNEUMONIA VIRUS OF MICE (PVM) AND INFLUENZA VIRUSES: THE EFFECTS OF pH AND ELECTROLYTES UPON VIRUS-HOST CELL COMBINATIONS
title_fullStr THE ASSOCIATIVE REACTIONS OF PNEUMONIA VIRUS OF MICE (PVM) AND INFLUENZA VIRUSES: THE EFFECTS OF pH AND ELECTROLYTES UPON VIRUS-HOST CELL COMBINATIONS
title_full_unstemmed THE ASSOCIATIVE REACTIONS OF PNEUMONIA VIRUS OF MICE (PVM) AND INFLUENZA VIRUSES: THE EFFECTS OF pH AND ELECTROLYTES UPON VIRUS-HOST CELL COMBINATIONS
title_short THE ASSOCIATIVE REACTIONS OF PNEUMONIA VIRUS OF MICE (PVM) AND INFLUENZA VIRUSES: THE EFFECTS OF pH AND ELECTROLYTES UPON VIRUS-HOST CELL COMBINATIONS
title_sort associative reactions of pneumonia virus of mice (pvm) and influenza viruses: the effects of ph and electrolytes upon virus-host cell combinations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135846/
https://www.ncbi.nlm.nih.gov/pubmed/18103399
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