THE NATURE OF THE VIRUS RECEPTORS OF RED CELLS : III. PARTIAL PURIFICATION OF THE VIRUS AGGLUTINATION INHIBITOR IN HUMAN PLASMA

A substance (VHI) exists in human plasma which inhibits the agglutination of red cells by influenza virus and is distinct from influenza antibody. When plasma is fractionated by alcohol in the cold the VHI comes out mainly with a mixture of lipid-free alpha and beta globulins (fraction IV-4). On fur...

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Autor principal: Hirst, George K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1949
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135861/
https://www.ncbi.nlm.nih.gov/pubmed/18123178
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author Hirst, George K.
author_facet Hirst, George K.
author_sort Hirst, George K.
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description A substance (VHI) exists in human plasma which inhibits the agglutination of red cells by influenza virus and is distinct from influenza antibody. When plasma is fractionated by alcohol in the cold the VHI comes out mainly with a mixture of lipid-free alpha and beta globulins (fraction IV-4). On further fractionation the activity comes out with a fraction consisting mainly of beta(1) globulin (fraction IV-7). Boiling fraction IV-4 or IV-7 after considerable dilution brings about a large increase in the amount of VHI, much more than can be detected in the original plasma. A similar VHI has been extracted from the ghosts of fowl red cells.
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spelling pubmed-21358612008-04-17 THE NATURE OF THE VIRUS RECEPTORS OF RED CELLS : III. PARTIAL PURIFICATION OF THE VIRUS AGGLUTINATION INHIBITOR IN HUMAN PLASMA Hirst, George K. J Exp Med Article A substance (VHI) exists in human plasma which inhibits the agglutination of red cells by influenza virus and is distinct from influenza antibody. When plasma is fractionated by alcohol in the cold the VHI comes out mainly with a mixture of lipid-free alpha and beta globulins (fraction IV-4). On further fractionation the activity comes out with a fraction consisting mainly of beta(1) globulin (fraction IV-7). Boiling fraction IV-4 or IV-7 after considerable dilution brings about a large increase in the amount of VHI, much more than can be detected in the original plasma. A similar VHI has been extracted from the ghosts of fowl red cells. The Rockefeller University Press 1949-01-31 /pmc/articles/PMC2135861/ /pubmed/18123178 Text en Copyright © Copyright, 1949, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hirst, George K.
THE NATURE OF THE VIRUS RECEPTORS OF RED CELLS : III. PARTIAL PURIFICATION OF THE VIRUS AGGLUTINATION INHIBITOR IN HUMAN PLASMA
title THE NATURE OF THE VIRUS RECEPTORS OF RED CELLS : III. PARTIAL PURIFICATION OF THE VIRUS AGGLUTINATION INHIBITOR IN HUMAN PLASMA
title_full THE NATURE OF THE VIRUS RECEPTORS OF RED CELLS : III. PARTIAL PURIFICATION OF THE VIRUS AGGLUTINATION INHIBITOR IN HUMAN PLASMA
title_fullStr THE NATURE OF THE VIRUS RECEPTORS OF RED CELLS : III. PARTIAL PURIFICATION OF THE VIRUS AGGLUTINATION INHIBITOR IN HUMAN PLASMA
title_full_unstemmed THE NATURE OF THE VIRUS RECEPTORS OF RED CELLS : III. PARTIAL PURIFICATION OF THE VIRUS AGGLUTINATION INHIBITOR IN HUMAN PLASMA
title_short THE NATURE OF THE VIRUS RECEPTORS OF RED CELLS : III. PARTIAL PURIFICATION OF THE VIRUS AGGLUTINATION INHIBITOR IN HUMAN PLASMA
title_sort nature of the virus receptors of red cells : iii. partial purification of the virus agglutination inhibitor in human plasma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135861/
https://www.ncbi.nlm.nih.gov/pubmed/18123178
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