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THE EFFECT OF LITHIUM PERIODATE ON CRYSTALLINE BOVINE SERUM ALBUMIN

A study of the chemical, physicochemical, and immunological changes in bovine serum albumin, brought about by oxidation with lithium periodate, has been made. It has been shown that destruction of certain amino acids occurs, that a change in the absorption spectrum takes place, and that the electrop...

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Detalles Bibliográficos
Autores principales: Goebel, Walther F., Perlmann, Gertrude E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1949
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135881/
https://www.ncbi.nlm.nih.gov/pubmed/18120090
Descripción
Sumario:A study of the chemical, physicochemical, and immunological changes in bovine serum albumin, brought about by oxidation with lithium periodate, has been made. It has been shown that destruction of certain amino acids occurs, that a change in the absorption spectrum takes place, and that the electrophoretic behavior of the protein is altered. Prolonged contact of bovine albumin with lithium periodate destroys its ability to incite antibodies in experimental animals.