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STUDIES ON HERPETIC INFECTION IN MICE : V. INFLUENCE OF ROUTE OF INOCULATION ON SUSCEPTIBILITY TO HERPETIC INFECTION; EFFECT OF AGE, AND OF METHYLCHOLANTHRENE

1. The severity of herpetic infection, of mice varied according to the site of inoculation, decreasing in the following order: cornea, skin of abdomen, pad of hind foot, tail. 2. The preliminary treatment of the foot pad or tail with methylcholanthrene increased the susceptibility to herpetic infect...

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Detalles Bibliográficos
Autores principales: Evans, Charles A., Slavin, Howard B., Berry, George Packer
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1950
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135977/
https://www.ncbi.nlm.nih.gov/pubmed/15415507
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author Evans, Charles A.
Slavin, Howard B.
Berry, George Packer
author_facet Evans, Charles A.
Slavin, Howard B.
Berry, George Packer
author_sort Evans, Charles A.
collection PubMed
description 1. The severity of herpetic infection, of mice varied according to the site of inoculation, decreasing in the following order: cornea, skin of abdomen, pad of hind foot, tail. 2. The preliminary treatment of the foot pad or tail with methylcholanthrene increased the susceptibility to herpetic infection to a limited extent. 3. Two-week-old mice showed a much greater susceptibility to herpes virus inoculated on the tail or on the pad of the hind foot than did adult mice. 4. The HF strain of herpes virus, after more than 125 serial brain-to-brain passages in mice, possessed high virulence for cutaneous tissues of mice and showed no important differences in this respect from a recently isolated strain (Klee) of herpes virus.
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spelling pubmed-21359772008-04-17 STUDIES ON HERPETIC INFECTION IN MICE : V. INFLUENCE OF ROUTE OF INOCULATION ON SUSCEPTIBILITY TO HERPETIC INFECTION; EFFECT OF AGE, AND OF METHYLCHOLANTHRENE Evans, Charles A. Slavin, Howard B. Berry, George Packer J Exp Med Article 1. The severity of herpetic infection, of mice varied according to the site of inoculation, decreasing in the following order: cornea, skin of abdomen, pad of hind foot, tail. 2. The preliminary treatment of the foot pad or tail with methylcholanthrene increased the susceptibility to herpetic infection to a limited extent. 3. Two-week-old mice showed a much greater susceptibility to herpes virus inoculated on the tail or on the pad of the hind foot than did adult mice. 4. The HF strain of herpes virus, after more than 125 serial brain-to-brain passages in mice, possessed high virulence for cutaneous tissues of mice and showed no important differences in this respect from a recently isolated strain (Klee) of herpes virus. The Rockefeller University Press 1950-05-01 /pmc/articles/PMC2135977/ /pubmed/15415507 Text en Copyright © Copyright, 1950, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Evans, Charles A.
Slavin, Howard B.
Berry, George Packer
STUDIES ON HERPETIC INFECTION IN MICE : V. INFLUENCE OF ROUTE OF INOCULATION ON SUSCEPTIBILITY TO HERPETIC INFECTION; EFFECT OF AGE, AND OF METHYLCHOLANTHRENE
title STUDIES ON HERPETIC INFECTION IN MICE : V. INFLUENCE OF ROUTE OF INOCULATION ON SUSCEPTIBILITY TO HERPETIC INFECTION; EFFECT OF AGE, AND OF METHYLCHOLANTHRENE
title_full STUDIES ON HERPETIC INFECTION IN MICE : V. INFLUENCE OF ROUTE OF INOCULATION ON SUSCEPTIBILITY TO HERPETIC INFECTION; EFFECT OF AGE, AND OF METHYLCHOLANTHRENE
title_fullStr STUDIES ON HERPETIC INFECTION IN MICE : V. INFLUENCE OF ROUTE OF INOCULATION ON SUSCEPTIBILITY TO HERPETIC INFECTION; EFFECT OF AGE, AND OF METHYLCHOLANTHRENE
title_full_unstemmed STUDIES ON HERPETIC INFECTION IN MICE : V. INFLUENCE OF ROUTE OF INOCULATION ON SUSCEPTIBILITY TO HERPETIC INFECTION; EFFECT OF AGE, AND OF METHYLCHOLANTHRENE
title_short STUDIES ON HERPETIC INFECTION IN MICE : V. INFLUENCE OF ROUTE OF INOCULATION ON SUSCEPTIBILITY TO HERPETIC INFECTION; EFFECT OF AGE, AND OF METHYLCHOLANTHRENE
title_sort studies on herpetic infection in mice : v. influence of route of inoculation on susceptibility to herpetic infection; effect of age, and of methylcholanthrene
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135977/
https://www.ncbi.nlm.nih.gov/pubmed/15415507
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