PRODUCTION OF THE SHWARTZMAN PHENOMENON BY A SINGLE-INJECTION TECHNIC

In the hypersensitive animal a single inoculation of homologous antigen mixed with Shwartzman preparatory toxin may lead to the production of a Shwartzman reaction which functions as an amplifier of the antigen-antibody tissue response. The combination of antigen and bacterial toxin does not alter t...

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Detalles Bibliográficos
Autores principales: Black-Schaffer, B., Milam, J. W., Brockman, D. D., Coonrad, E. V., Silverman, S. B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1950
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135984/
https://www.ncbi.nlm.nih.gov/pubmed/15415508
Descripción
Sumario:In the hypersensitive animal a single inoculation of homologous antigen mixed with Shwartzman preparatory toxin may lead to the production of a Shwartzman reaction which functions as an amplifier of the antigen-antibody tissue response. The combination of antigen and bacterial toxin does not alter the antigenicity of purified bovine gamma globulin. This form of the Shwartzman phenomenon may be useful in the investigation of hyperergic tissue reactions.

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