PRODUCTION OF THE SHWARTZMAN PHENOMENON BY A SINGLE-INJECTION TECHNIC

In the hypersensitive animal a single inoculation of homologous antigen mixed with Shwartzman preparatory toxin may lead to the production of a Shwartzman reaction which functions as an amplifier of the antigen-antibody tissue response. The combination of antigen and bacterial toxin does not alter t...

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Autores principales: Black-Schaffer, B., Milam, J. W., Brockman, D. D., Coonrad, E. V., Silverman, S. B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1950
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135984/
https://www.ncbi.nlm.nih.gov/pubmed/15415508
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author Black-Schaffer, B.
Milam, J. W.
Brockman, D. D.
Coonrad, E. V.
Silverman, S. B.
author_facet Black-Schaffer, B.
Milam, J. W.
Brockman, D. D.
Coonrad, E. V.
Silverman, S. B.
author_sort Black-Schaffer, B.
collection PubMed
description In the hypersensitive animal a single inoculation of homologous antigen mixed with Shwartzman preparatory toxin may lead to the production of a Shwartzman reaction which functions as an amplifier of the antigen-antibody tissue response. The combination of antigen and bacterial toxin does not alter the antigenicity of purified bovine gamma globulin. This form of the Shwartzman phenomenon may be useful in the investigation of hyperergic tissue reactions.
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spelling pubmed-21359842008-04-17 PRODUCTION OF THE SHWARTZMAN PHENOMENON BY A SINGLE-INJECTION TECHNIC Black-Schaffer, B. Milam, J. W. Brockman, D. D. Coonrad, E. V. Silverman, S. B. J Exp Med Article In the hypersensitive animal a single inoculation of homologous antigen mixed with Shwartzman preparatory toxin may lead to the production of a Shwartzman reaction which functions as an amplifier of the antigen-antibody tissue response. The combination of antigen and bacterial toxin does not alter the antigenicity of purified bovine gamma globulin. This form of the Shwartzman phenomenon may be useful in the investigation of hyperergic tissue reactions. The Rockefeller University Press 1950-05-01 /pmc/articles/PMC2135984/ /pubmed/15415508 Text en Copyright © Copyright, 1950, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Black-Schaffer, B.
Milam, J. W.
Brockman, D. D.
Coonrad, E. V.
Silverman, S. B.
PRODUCTION OF THE SHWARTZMAN PHENOMENON BY A SINGLE-INJECTION TECHNIC
title PRODUCTION OF THE SHWARTZMAN PHENOMENON BY A SINGLE-INJECTION TECHNIC
title_full PRODUCTION OF THE SHWARTZMAN PHENOMENON BY A SINGLE-INJECTION TECHNIC
title_fullStr PRODUCTION OF THE SHWARTZMAN PHENOMENON BY A SINGLE-INJECTION TECHNIC
title_full_unstemmed PRODUCTION OF THE SHWARTZMAN PHENOMENON BY A SINGLE-INJECTION TECHNIC
title_short PRODUCTION OF THE SHWARTZMAN PHENOMENON BY A SINGLE-INJECTION TECHNIC
title_sort production of the shwartzman phenomenon by a single-injection technic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135984/
https://www.ncbi.nlm.nih.gov/pubmed/15415508
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