EFFECT OF THE REMOVAL OF LIPIDS ON SPECIFIC PRECIPITATION

Horse antisera to rabbit albumin and globulins and to Type III pneumococci were extracted at low temperatures with alcohol-ether. The precipitin reactions given by these sera deprived of lipids were studied by quantitative analytical methods. With longer periods of standing and slightly higher speed...

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Detalles Bibliográficos
Autores principales: Krueger, Robert C., Heidelberger, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1950
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135985/
https://www.ncbi.nlm.nih.gov/pubmed/14778919
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author Krueger, Robert C.
Heidelberger, Michael
author_facet Krueger, Robert C.
Heidelberger, Michael
author_sort Krueger, Robert C.
collection PubMed
description Horse antisera to rabbit albumin and globulins and to Type III pneumococci were extracted at low temperatures with alcohol-ether. The precipitin reactions given by these sera deprived of lipids were studied by quantitative analytical methods. With longer periods of standing and slightly higher speeds of centrifugation than those usually required for lipid-containing sera, precipitation may be made complete in immune sera from which the lipids have been removed. The function of lipids in immune reactions is discussed, as well as the effects on antibody globulin of the procedures used in their removal.
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spelling pubmed-21359852008-04-17 EFFECT OF THE REMOVAL OF LIPIDS ON SPECIFIC PRECIPITATION Krueger, Robert C. Heidelberger, Michael J Exp Med Article Horse antisera to rabbit albumin and globulins and to Type III pneumococci were extracted at low temperatures with alcohol-ether. The precipitin reactions given by these sera deprived of lipids were studied by quantitative analytical methods. With longer periods of standing and slightly higher speeds of centrifugation than those usually required for lipid-containing sera, precipitation may be made complete in immune sera from which the lipids have been removed. The function of lipids in immune reactions is discussed, as well as the effects on antibody globulin of the procedures used in their removal. The Rockefeller University Press 1950-10-31 /pmc/articles/PMC2135985/ /pubmed/14778919 Text en Copyright © Copyright, 1950, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Krueger, Robert C.
Heidelberger, Michael
EFFECT OF THE REMOVAL OF LIPIDS ON SPECIFIC PRECIPITATION
title EFFECT OF THE REMOVAL OF LIPIDS ON SPECIFIC PRECIPITATION
title_full EFFECT OF THE REMOVAL OF LIPIDS ON SPECIFIC PRECIPITATION
title_fullStr EFFECT OF THE REMOVAL OF LIPIDS ON SPECIFIC PRECIPITATION
title_full_unstemmed EFFECT OF THE REMOVAL OF LIPIDS ON SPECIFIC PRECIPITATION
title_short EFFECT OF THE REMOVAL OF LIPIDS ON SPECIFIC PRECIPITATION
title_sort effect of the removal of lipids on specific precipitation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135985/
https://www.ncbi.nlm.nih.gov/pubmed/14778919
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AT heidelbergermichael effectoftheremovaloflipidsonspecificprecipitation

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