RELATION OF VIRULENCE OF PNEUMOCOCCAL STRAINS FOR MICE TO THE QUANTITY OF CAPSULAR POLYSACCHARIDE FORMED IN VITRO

The amount of capsular polysaccharide formed in vitro by strains of pneumococcus types II, III, and VII of different virulence for mice has been measured by quantitative precipitin reactions. The quantity produced by strains of high virulence was greater for all three types than that formed by moder...

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Detalles Bibliográficos
Autores principales: MacLeod, Colin M., Krauss, Marjorie R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1950
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136027/
https://www.ncbi.nlm.nih.gov/pubmed/15422092
Descripción
Sumario:The amount of capsular polysaccharide formed in vitro by strains of pneumococcus types II, III, and VII of different virulence for mice has been measured by quantitative precipitin reactions. The quantity produced by strains of high virulence was greater for all three types than that formed by moderately virulent or avirulent strains. It is suggested that an important factor concerned in variations of virulence of pneumococci for mice is the genetic apparatus that controls the amount of SSS synthesized by the cells.

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