THE EFFECT OF CORTISONE AND ADRENOCORTICOTROPHIC HORMONE ON THE CONCENTRATION OF CIRCULATING ANTIBODY

The administration of adrenocorticotrophic hormone and of cortisone was found to result in a reduction in the concentration of antipneumococcal antibody in the circulation of rabbits. This reduction occurred both when the hormones were administered at the beginning of immunization and after immuniza...

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Detalles Bibliográficos
Autores principales: Bjørneboe, Mogens, Fischel, Edward E., Stoerk, Herbert C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1951
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136054/
https://www.ncbi.nlm.nih.gov/pubmed/14803630
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author Bjørneboe, Mogens
Fischel, Edward E.
Stoerk, Herbert C.
author_facet Bjørneboe, Mogens
Fischel, Edward E.
Stoerk, Herbert C.
author_sort Bjørneboe, Mogens
collection PubMed
description The administration of adrenocorticotrophic hormone and of cortisone was found to result in a reduction in the concentration of antipneumococcal antibody in the circulation of rabbits. This reduction occurred both when the hormones were administered at the beginning of immunization and after immunization was well advanced. Marked atrophic changes in lymphoid tissue and a diminution in the number of various types of mononuclear cells followed upon the hormone administration. The possible bearing of these observations on theories concerning the sites of antibody production is discussed.
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spelling pubmed-21360542008-04-17 THE EFFECT OF CORTISONE AND ADRENOCORTICOTROPHIC HORMONE ON THE CONCENTRATION OF CIRCULATING ANTIBODY Bjørneboe, Mogens Fischel, Edward E. Stoerk, Herbert C. J Exp Med Article The administration of adrenocorticotrophic hormone and of cortisone was found to result in a reduction in the concentration of antipneumococcal antibody in the circulation of rabbits. This reduction occurred both when the hormones were administered at the beginning of immunization and after immunization was well advanced. Marked atrophic changes in lymphoid tissue and a diminution in the number of various types of mononuclear cells followed upon the hormone administration. The possible bearing of these observations on theories concerning the sites of antibody production is discussed. The Rockefeller University Press 1951-01-01 /pmc/articles/PMC2136054/ /pubmed/14803630 Text en Copyright © Copyright, 1951, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Bjørneboe, Mogens
Fischel, Edward E.
Stoerk, Herbert C.
THE EFFECT OF CORTISONE AND ADRENOCORTICOTROPHIC HORMONE ON THE CONCENTRATION OF CIRCULATING ANTIBODY
title THE EFFECT OF CORTISONE AND ADRENOCORTICOTROPHIC HORMONE ON THE CONCENTRATION OF CIRCULATING ANTIBODY
title_full THE EFFECT OF CORTISONE AND ADRENOCORTICOTROPHIC HORMONE ON THE CONCENTRATION OF CIRCULATING ANTIBODY
title_fullStr THE EFFECT OF CORTISONE AND ADRENOCORTICOTROPHIC HORMONE ON THE CONCENTRATION OF CIRCULATING ANTIBODY
title_full_unstemmed THE EFFECT OF CORTISONE AND ADRENOCORTICOTROPHIC HORMONE ON THE CONCENTRATION OF CIRCULATING ANTIBODY
title_short THE EFFECT OF CORTISONE AND ADRENOCORTICOTROPHIC HORMONE ON THE CONCENTRATION OF CIRCULATING ANTIBODY
title_sort effect of cortisone and adrenocorticotrophic hormone on the concentration of circulating antibody
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136054/
https://www.ncbi.nlm.nih.gov/pubmed/14803630
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