A MICROSPECTROPHOTOMETRIC STUDY OF RED CELL NUCLEI DURING PYKNOSIS

1. A microspectrophotometric apparatus was used to measure nuclear absorption in fixed and stained human bone marrow smears. 2. The validity of the measurements was established. 3. The total and polymerized desoxyribose nucleic acid (DNA) of erythroblast nuclei were measured in relative units, and a...

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Detalles Bibliográficos
Autor principal: Korson, Roy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1951
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136063/
https://www.ncbi.nlm.nih.gov/pubmed/14803636
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author Korson, Roy
author_facet Korson, Roy
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description 1. A microspectrophotometric apparatus was used to measure nuclear absorption in fixed and stained human bone marrow smears. 2. The validity of the measurements was established. 3. The total and polymerized desoxyribose nucleic acid (DNA) of erythroblast nuclei were measured in relative units, and a gradual loss of DNA from the red cell nucleus during maturation was noted. 4. The loss in DNA is comparable quantitatively to that occurring during pathological pyknosis in sarcoma cells. 5. The continual loss of nuclear material during erythropoiesis supports the conception that the nucleus disappears by intracellular dissolution, not by extrusion in the intact form.
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spelling pubmed-21360632008-04-17 A MICROSPECTROPHOTOMETRIC STUDY OF RED CELL NUCLEI DURING PYKNOSIS Korson, Roy J Exp Med Article 1. A microspectrophotometric apparatus was used to measure nuclear absorption in fixed and stained human bone marrow smears. 2. The validity of the measurements was established. 3. The total and polymerized desoxyribose nucleic acid (DNA) of erythroblast nuclei were measured in relative units, and a gradual loss of DNA from the red cell nucleus during maturation was noted. 4. The loss in DNA is comparable quantitatively to that occurring during pathological pyknosis in sarcoma cells. 5. The continual loss of nuclear material during erythropoiesis supports the conception that the nucleus disappears by intracellular dissolution, not by extrusion in the intact form. The Rockefeller University Press 1951-01-31 /pmc/articles/PMC2136063/ /pubmed/14803636 Text en Copyright © Copyright, 1951, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Korson, Roy
A MICROSPECTROPHOTOMETRIC STUDY OF RED CELL NUCLEI DURING PYKNOSIS
title A MICROSPECTROPHOTOMETRIC STUDY OF RED CELL NUCLEI DURING PYKNOSIS
title_full A MICROSPECTROPHOTOMETRIC STUDY OF RED CELL NUCLEI DURING PYKNOSIS
title_fullStr A MICROSPECTROPHOTOMETRIC STUDY OF RED CELL NUCLEI DURING PYKNOSIS
title_full_unstemmed A MICROSPECTROPHOTOMETRIC STUDY OF RED CELL NUCLEI DURING PYKNOSIS
title_short A MICROSPECTROPHOTOMETRIC STUDY OF RED CELL NUCLEI DURING PYKNOSIS
title_sort microspectrophotometric study of red cell nuclei during pyknosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136063/
https://www.ncbi.nlm.nih.gov/pubmed/14803636
work_keys_str_mv AT korsonroy amicrospectrophotometricstudyofredcellnucleiduringpyknosis
AT korsonroy microspectrophotometricstudyofredcellnucleiduringpyknosis

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