MECHANISM OF PROTEINURIA : III. A COMPARISON OF THE FUNCTIONAL AND STRUCTURAL ASPECTS OF THE EFFECTS OF CERTAIN INTRAPERITONEALLY ADMINISTERED PROTEINS ON HEMOGLOBIN EXCRETION IN THE RAT

Intraperitoneal administration of bovine albumin sharply increases glomerular permeability to hemoglobin in the rat kidney. In addition, bovine albumin "saturates" the tubular absorption mechanism and inhibits the tubular absorption of subsequently administered hemoglobin. Egg white, ovalb...

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Detalles Bibliográficos
Autores principales: Lippman, Richard W., Ureen, Helen J., Oliver, Jean
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1951
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136081/
https://www.ncbi.nlm.nih.gov/pubmed/14824405
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author Lippman, Richard W.
Ureen, Helen J.
Oliver, Jean
author_facet Lippman, Richard W.
Ureen, Helen J.
Oliver, Jean
author_sort Lippman, Richard W.
collection PubMed
description Intraperitoneal administration of bovine albumin sharply increases glomerular permeability to hemoglobin in the rat kidney. In addition, bovine albumin "saturates" the tubular absorption mechanism and inhibits the tubular absorption of subsequently administered hemoglobin. Egg white, ovalbumin, and ovomucoid, in contrast, do not produce significant changes in glomerular permeability to hemoglobin or in the tubular absorption of hemoglobin. These effects have been demonstrated both by physiologic measurements and by the morphologic demonstration of the absorbed proteins.
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spelling pubmed-21360812008-04-17 MECHANISM OF PROTEINURIA : III. A COMPARISON OF THE FUNCTIONAL AND STRUCTURAL ASPECTS OF THE EFFECTS OF CERTAIN INTRAPERITONEALLY ADMINISTERED PROTEINS ON HEMOGLOBIN EXCRETION IN THE RAT Lippman, Richard W. Ureen, Helen J. Oliver, Jean J Exp Med Article Intraperitoneal administration of bovine albumin sharply increases glomerular permeability to hemoglobin in the rat kidney. In addition, bovine albumin "saturates" the tubular absorption mechanism and inhibits the tubular absorption of subsequently administered hemoglobin. Egg white, ovalbumin, and ovomucoid, in contrast, do not produce significant changes in glomerular permeability to hemoglobin or in the tubular absorption of hemoglobin. These effects have been demonstrated both by physiologic measurements and by the morphologic demonstration of the absorbed proteins. The Rockefeller University Press 1951-03-31 /pmc/articles/PMC2136081/ /pubmed/14824405 Text en Copyright © Copyright, 1951, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Lippman, Richard W.
Ureen, Helen J.
Oliver, Jean
MECHANISM OF PROTEINURIA : III. A COMPARISON OF THE FUNCTIONAL AND STRUCTURAL ASPECTS OF THE EFFECTS OF CERTAIN INTRAPERITONEALLY ADMINISTERED PROTEINS ON HEMOGLOBIN EXCRETION IN THE RAT
title MECHANISM OF PROTEINURIA : III. A COMPARISON OF THE FUNCTIONAL AND STRUCTURAL ASPECTS OF THE EFFECTS OF CERTAIN INTRAPERITONEALLY ADMINISTERED PROTEINS ON HEMOGLOBIN EXCRETION IN THE RAT
title_full MECHANISM OF PROTEINURIA : III. A COMPARISON OF THE FUNCTIONAL AND STRUCTURAL ASPECTS OF THE EFFECTS OF CERTAIN INTRAPERITONEALLY ADMINISTERED PROTEINS ON HEMOGLOBIN EXCRETION IN THE RAT
title_fullStr MECHANISM OF PROTEINURIA : III. A COMPARISON OF THE FUNCTIONAL AND STRUCTURAL ASPECTS OF THE EFFECTS OF CERTAIN INTRAPERITONEALLY ADMINISTERED PROTEINS ON HEMOGLOBIN EXCRETION IN THE RAT
title_full_unstemmed MECHANISM OF PROTEINURIA : III. A COMPARISON OF THE FUNCTIONAL AND STRUCTURAL ASPECTS OF THE EFFECTS OF CERTAIN INTRAPERITONEALLY ADMINISTERED PROTEINS ON HEMOGLOBIN EXCRETION IN THE RAT
title_short MECHANISM OF PROTEINURIA : III. A COMPARISON OF THE FUNCTIONAL AND STRUCTURAL ASPECTS OF THE EFFECTS OF CERTAIN INTRAPERITONEALLY ADMINISTERED PROTEINS ON HEMOGLOBIN EXCRETION IN THE RAT
title_sort mechanism of proteinuria : iii. a comparison of the functional and structural aspects of the effects of certain intraperitoneally administered proteins on hemoglobin excretion in the rat
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136081/
https://www.ncbi.nlm.nih.gov/pubmed/14824405
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AT ureenhelenj mechanismofproteinuriaiiiacomparisonofthefunctionalandstructuralaspectsoftheeffectsofcertainintraperitoneallyadministeredproteinsonhemoglobinexcretionintherat
AT oliverjean mechanismofproteinuriaiiiacomparisonofthefunctionalandstructuralaspectsoftheeffectsofcertainintraperitoneallyadministeredproteinsonhemoglobinexcretionintherat

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