KINETIC STUDIES ON IMMUNE HEMOLYSIS : II. THE REVERSIBILITY OF RED CELL-ANTIBODY COMBINATION AND THE RESULTANT TRANSFER OF ANTIBODY FROM CELL TO CELL DURING HEMOLYSIS

The reversibility of the red cell-antibody combination has been demonstrated by means of experiments showing the transfer of antibody, either from red cell stromata to intact red cells, or from red cell to red cell. The extent of reversibility is variable with respect to different antisera. The tran...

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Detalles Bibliográficos
Autores principales: Bowman, Walter M., Mayer, Manfred M., Rapp, Herbert J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1951
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136101/
https://www.ncbi.nlm.nih.gov/pubmed/14861372
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author Bowman, Walter M.
Mayer, Manfred M.
Rapp, Herbert J.
author_facet Bowman, Walter M.
Mayer, Manfred M.
Rapp, Herbert J.
author_sort Bowman, Walter M.
collection PubMed
description The reversibility of the red cell-antibody combination has been demonstrated by means of experiments showing the transfer of antibody, either from red cell stromata to intact red cells, or from red cell to red cell. The extent of reversibility is variable with respect to different antisera. The transfer of antibody from stromata to intact red cells is not dependent upon the action of complement. Transfer of antibody can also take place after interaction of the stromata-antibody complex with complement. As a result, antibody molecules can perform hemolytic work over and over again, provided complement is available, and this leads to kinetic behavior of a catalytic character.
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spelling pubmed-21361012008-04-17 KINETIC STUDIES ON IMMUNE HEMOLYSIS : II. THE REVERSIBILITY OF RED CELL-ANTIBODY COMBINATION AND THE RESULTANT TRANSFER OF ANTIBODY FROM CELL TO CELL DURING HEMOLYSIS Bowman, Walter M. Mayer, Manfred M. Rapp, Herbert J. J Exp Med Article The reversibility of the red cell-antibody combination has been demonstrated by means of experiments showing the transfer of antibody, either from red cell stromata to intact red cells, or from red cell to red cell. The extent of reversibility is variable with respect to different antisera. The transfer of antibody from stromata to intact red cells is not dependent upon the action of complement. Transfer of antibody can also take place after interaction of the stromata-antibody complex with complement. As a result, antibody molecules can perform hemolytic work over and over again, provided complement is available, and this leads to kinetic behavior of a catalytic character. The Rockefeller University Press 1951-08-01 /pmc/articles/PMC2136101/ /pubmed/14861372 Text en Copyright © Copyright, 1951, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Bowman, Walter M.
Mayer, Manfred M.
Rapp, Herbert J.
KINETIC STUDIES ON IMMUNE HEMOLYSIS : II. THE REVERSIBILITY OF RED CELL-ANTIBODY COMBINATION AND THE RESULTANT TRANSFER OF ANTIBODY FROM CELL TO CELL DURING HEMOLYSIS
title KINETIC STUDIES ON IMMUNE HEMOLYSIS : II. THE REVERSIBILITY OF RED CELL-ANTIBODY COMBINATION AND THE RESULTANT TRANSFER OF ANTIBODY FROM CELL TO CELL DURING HEMOLYSIS
title_full KINETIC STUDIES ON IMMUNE HEMOLYSIS : II. THE REVERSIBILITY OF RED CELL-ANTIBODY COMBINATION AND THE RESULTANT TRANSFER OF ANTIBODY FROM CELL TO CELL DURING HEMOLYSIS
title_fullStr KINETIC STUDIES ON IMMUNE HEMOLYSIS : II. THE REVERSIBILITY OF RED CELL-ANTIBODY COMBINATION AND THE RESULTANT TRANSFER OF ANTIBODY FROM CELL TO CELL DURING HEMOLYSIS
title_full_unstemmed KINETIC STUDIES ON IMMUNE HEMOLYSIS : II. THE REVERSIBILITY OF RED CELL-ANTIBODY COMBINATION AND THE RESULTANT TRANSFER OF ANTIBODY FROM CELL TO CELL DURING HEMOLYSIS
title_short KINETIC STUDIES ON IMMUNE HEMOLYSIS : II. THE REVERSIBILITY OF RED CELL-ANTIBODY COMBINATION AND THE RESULTANT TRANSFER OF ANTIBODY FROM CELL TO CELL DURING HEMOLYSIS
title_sort kinetic studies on immune hemolysis : ii. the reversibility of red cell-antibody combination and the resultant transfer of antibody from cell to cell during hemolysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136101/
https://www.ncbi.nlm.nih.gov/pubmed/14861372
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AT mayermanfredm kineticstudiesonimmunehemolysisiithereversibilityofredcellantibodycombinationandtheresultanttransferofantibodyfromcelltocellduringhemolysis
AT rappherbertj kineticstudiesonimmunehemolysisiithereversibilityofredcellantibodycombinationandtheresultanttransferofantibodyfromcelltocellduringhemolysis

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