STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES : III. THE PROPAGATION OF POLIOMYELITIS VIRUSES IN TISSUE CULTURES DEVOID OF NERVE CELLS

Cells like fibroblasts, having no resemblance whatever to nerve cells were obtained in morphologically pure cultures from monkey testicular tissue and were found to support the growth in vitro of poliomyelitis virus, Type 2, Yale-SK strain. Moreover, these cells were destroyed as a result of the mul...

Descripción completa

Detalles Bibliográficos
Autores principales: Scherer, William F., Syverton, Jerome T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1952
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136151/
https://www.ncbi.nlm.nih.gov/pubmed/12981222
_version_ 1782143061545975808
author Scherer, William F.
Syverton, Jerome T.
author_facet Scherer, William F.
Syverton, Jerome T.
author_sort Scherer, William F.
collection PubMed
description Cells like fibroblasts, having no resemblance whatever to nerve cells were obtained in morphologically pure cultures from monkey testicular tissue and were found to support the growth in vitro of poliomyelitis virus, Type 2, Yale-SK strain. Moreover, these cells were destroyed as a result of the multiplication of this virus within them. Similarly, "fibroblasts" propagated in primary explant cultures of testicle were destroyed by poliomyelitis viruses, Types 1 and 2. Type specific antibodies neutralized the pathogenic effect of poliomyelitis virus on monkey testicular fibroblasts.
format Text
id pubmed-2136151
institution National Center for Biotechnology Information
language English
publishDate 1952
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21361512008-04-17 STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES : III. THE PROPAGATION OF POLIOMYELITIS VIRUSES IN TISSUE CULTURES DEVOID OF NERVE CELLS Scherer, William F. Syverton, Jerome T. J Exp Med Article Cells like fibroblasts, having no resemblance whatever to nerve cells were obtained in morphologically pure cultures from monkey testicular tissue and were found to support the growth in vitro of poliomyelitis virus, Type 2, Yale-SK strain. Moreover, these cells were destroyed as a result of the multiplication of this virus within them. Similarly, "fibroblasts" propagated in primary explant cultures of testicle were destroyed by poliomyelitis viruses, Types 1 and 2. Type specific antibodies neutralized the pathogenic effect of poliomyelitis virus on monkey testicular fibroblasts. The Rockefeller University Press 1952-09-30 /pmc/articles/PMC2136151/ /pubmed/12981222 Text en Copyright © Copyright, 1952, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Scherer, William F.
Syverton, Jerome T.
STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES : III. THE PROPAGATION OF POLIOMYELITIS VIRUSES IN TISSUE CULTURES DEVOID OF NERVE CELLS
title STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES : III. THE PROPAGATION OF POLIOMYELITIS VIRUSES IN TISSUE CULTURES DEVOID OF NERVE CELLS
title_full STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES : III. THE PROPAGATION OF POLIOMYELITIS VIRUSES IN TISSUE CULTURES DEVOID OF NERVE CELLS
title_fullStr STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES : III. THE PROPAGATION OF POLIOMYELITIS VIRUSES IN TISSUE CULTURES DEVOID OF NERVE CELLS
title_full_unstemmed STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES : III. THE PROPAGATION OF POLIOMYELITIS VIRUSES IN TISSUE CULTURES DEVOID OF NERVE CELLS
title_short STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES : III. THE PROPAGATION OF POLIOMYELITIS VIRUSES IN TISSUE CULTURES DEVOID OF NERVE CELLS
title_sort studies on the propagation in vitro of poliomyelitis viruses : iii. the propagation of poliomyelitis viruses in tissue cultures devoid of nerve cells
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136151/
https://www.ncbi.nlm.nih.gov/pubmed/12981222
work_keys_str_mv AT schererwilliamf studiesonthepropagationinvitroofpoliomyelitisvirusesiiithepropagationofpoliomyelitisvirusesintissueculturesdevoidofnervecells
AT syvertonjeromet studiesonthepropagationinvitroofpoliomyelitisvirusesiiithepropagationofpoliomyelitisvirusesintissueculturesdevoidofnervecells

Ejemplares similares