THE HALF-LIFE OF HOMOLOGOUS GAMMA GLOBULIN (ANTIBODY) IN SEVERAL SPECIES

1. The half-lives of homologous gamma globulins labelled with I(131) agree well with the half-lives of passively administered homologous antibodies and provide a simple, quantitative tool for the determination of antibody half-life when immunochemical techniques are difficult to apply. 2. The half-l...

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Detalles Bibliográficos
Autores principales: Dixon, Frank J., Talmage, David W., Maurer, Paul H., Deichmiller, Maria
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1952
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136155/
https://www.ncbi.nlm.nih.gov/pubmed/12981216
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author Dixon, Frank J.
Talmage, David W.
Maurer, Paul H.
Deichmiller, Maria
author_facet Dixon, Frank J.
Talmage, David W.
Maurer, Paul H.
Deichmiller, Maria
author_sort Dixon, Frank J.
collection PubMed
description 1. The half-lives of homologous gamma globulins labelled with I(131) agree well with the half-lives of passively administered homologous antibodies and provide a simple, quantitative tool for the determination of antibody half-life when immunochemical techniques are difficult to apply. 2. The half-lives of gamma globulin or antibody vary markedly from species to species and apparently even among age groups within a species. 3. The half-lives of gamma globulin or antibody seem to be dependent, at least in part, on the metabolic rate of the host.
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spelling pubmed-21361552008-04-17 THE HALF-LIFE OF HOMOLOGOUS GAMMA GLOBULIN (ANTIBODY) IN SEVERAL SPECIES Dixon, Frank J. Talmage, David W. Maurer, Paul H. Deichmiller, Maria J Exp Med Article 1. The half-lives of homologous gamma globulins labelled with I(131) agree well with the half-lives of passively administered homologous antibodies and provide a simple, quantitative tool for the determination of antibody half-life when immunochemical techniques are difficult to apply. 2. The half-lives of gamma globulin or antibody vary markedly from species to species and apparently even among age groups within a species. 3. The half-lives of gamma globulin or antibody seem to be dependent, at least in part, on the metabolic rate of the host. The Rockefeller University Press 1952-09-30 /pmc/articles/PMC2136155/ /pubmed/12981216 Text en Copyright © Copyright, 1952, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Dixon, Frank J.
Talmage, David W.
Maurer, Paul H.
Deichmiller, Maria
THE HALF-LIFE OF HOMOLOGOUS GAMMA GLOBULIN (ANTIBODY) IN SEVERAL SPECIES
title THE HALF-LIFE OF HOMOLOGOUS GAMMA GLOBULIN (ANTIBODY) IN SEVERAL SPECIES
title_full THE HALF-LIFE OF HOMOLOGOUS GAMMA GLOBULIN (ANTIBODY) IN SEVERAL SPECIES
title_fullStr THE HALF-LIFE OF HOMOLOGOUS GAMMA GLOBULIN (ANTIBODY) IN SEVERAL SPECIES
title_full_unstemmed THE HALF-LIFE OF HOMOLOGOUS GAMMA GLOBULIN (ANTIBODY) IN SEVERAL SPECIES
title_short THE HALF-LIFE OF HOMOLOGOUS GAMMA GLOBULIN (ANTIBODY) IN SEVERAL SPECIES
title_sort half-life of homologous gamma globulin (antibody) in several species
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136155/
https://www.ncbi.nlm.nih.gov/pubmed/12981216
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