ADAPTATION OF GROUP B COXSACKIE VIRUS TO ADULT MOUSE PANCREAS

An alteration of tissue tropism of a Coxsackie virus has been observed following different methods of propagation of the virus in animals. Tropism for the adult mouse pancreas, as described by Pappenheimer, appeared to be irrevocably lost following prolonged brain-to-brain transfer. It was present i...

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Detalles Bibliográficos
Autores principales: Dalldorf, Gilbert, Gifford, Rebecca
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1952
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136156/
https://www.ncbi.nlm.nih.gov/pubmed/13000059
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author Dalldorf, Gilbert
Gifford, Rebecca
author_facet Dalldorf, Gilbert
Gifford, Rebecca
author_sort Dalldorf, Gilbert
collection PubMed
description An alteration of tissue tropism of a Coxsackie virus has been observed following different methods of propagation of the virus in animals. Tropism for the adult mouse pancreas, as described by Pappenheimer, appeared to be irrevocably lost following prolonged brain-to-brain transfer. It was present in the same strain on reisolation from human feces, was intensified following pancreas transfers, and suppressed by brain transfers. Pancreatotropism may be correlated with the titer of virus in the pancreas.
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spelling pubmed-21361562008-04-17 ADAPTATION OF GROUP B COXSACKIE VIRUS TO ADULT MOUSE PANCREAS Dalldorf, Gilbert Gifford, Rebecca J Exp Med Article An alteration of tissue tropism of a Coxsackie virus has been observed following different methods of propagation of the virus in animals. Tropism for the adult mouse pancreas, as described by Pappenheimer, appeared to be irrevocably lost following prolonged brain-to-brain transfer. It was present in the same strain on reisolation from human feces, was intensified following pancreas transfers, and suppressed by brain transfers. Pancreatotropism may be correlated with the titer of virus in the pancreas. The Rockefeller University Press 1952-10-31 /pmc/articles/PMC2136156/ /pubmed/13000059 Text en Copyright © Copyright, 1952, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Dalldorf, Gilbert
Gifford, Rebecca
ADAPTATION OF GROUP B COXSACKIE VIRUS TO ADULT MOUSE PANCREAS
title ADAPTATION OF GROUP B COXSACKIE VIRUS TO ADULT MOUSE PANCREAS
title_full ADAPTATION OF GROUP B COXSACKIE VIRUS TO ADULT MOUSE PANCREAS
title_fullStr ADAPTATION OF GROUP B COXSACKIE VIRUS TO ADULT MOUSE PANCREAS
title_full_unstemmed ADAPTATION OF GROUP B COXSACKIE VIRUS TO ADULT MOUSE PANCREAS
title_short ADAPTATION OF GROUP B COXSACKIE VIRUS TO ADULT MOUSE PANCREAS
title_sort adaptation of group b coxsackie virus to adult mouse pancreas
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136156/
https://www.ncbi.nlm.nih.gov/pubmed/13000059
work_keys_str_mv AT dalldorfgilbert adaptationofgroupbcoxsackievirustoadultmousepancreas
AT giffordrebecca adaptationofgroupbcoxsackievirustoadultmousepancreas

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