STUDIES ON THE EXTRACELLULAR CULTIVATION OF AN INTRACELLULAR PARASITE (AVIAN MALARIA) : II. THE EFFECTS OF MALATE AND OF COENZYME A CONCENTRATES

The extracellular survival and development in vitro of the erythrocytic stages of Plasmodium lophurae were favored by the addition to the culture medium of l-malic acid and concentrates rich in coenzyme A. In a concentrated extract of duck erythrocytes supplemented with these two substances in addit...

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Detalles Bibliográficos
Autor principal: Trager, William
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1952
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136161/
https://www.ncbi.nlm.nih.gov/pubmed/13000057
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author Trager, William
author_facet Trager, William
author_sort Trager, William
collection PubMed
description The extracellular survival and development in vitro of the erythrocytic stages of Plasmodium lophurae were favored by the addition to the culture medium of l-malic acid and concentrates rich in coenzyme A. In a concentrated extract of duck erythrocytes supplemented with these two substances in addition to adenosinetriphosphate, sodium pyruvate, and certain other materials of like nature, only 5 to 10 per cent of the extracellular parasites had become abnormal after 3 days of cultivation.
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spelling pubmed-21361612008-04-17 STUDIES ON THE EXTRACELLULAR CULTIVATION OF AN INTRACELLULAR PARASITE (AVIAN MALARIA) : II. THE EFFECTS OF MALATE AND OF COENZYME A CONCENTRATES Trager, William J Exp Med Article The extracellular survival and development in vitro of the erythrocytic stages of Plasmodium lophurae were favored by the addition to the culture medium of l-malic acid and concentrates rich in coenzyme A. In a concentrated extract of duck erythrocytes supplemented with these two substances in addition to adenosinetriphosphate, sodium pyruvate, and certain other materials of like nature, only 5 to 10 per cent of the extracellular parasites had become abnormal after 3 days of cultivation. The Rockefeller University Press 1952-10-31 /pmc/articles/PMC2136161/ /pubmed/13000057 Text en Copyright © Copyright, 1952, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Trager, William
STUDIES ON THE EXTRACELLULAR CULTIVATION OF AN INTRACELLULAR PARASITE (AVIAN MALARIA) : II. THE EFFECTS OF MALATE AND OF COENZYME A CONCENTRATES
title STUDIES ON THE EXTRACELLULAR CULTIVATION OF AN INTRACELLULAR PARASITE (AVIAN MALARIA) : II. THE EFFECTS OF MALATE AND OF COENZYME A CONCENTRATES
title_full STUDIES ON THE EXTRACELLULAR CULTIVATION OF AN INTRACELLULAR PARASITE (AVIAN MALARIA) : II. THE EFFECTS OF MALATE AND OF COENZYME A CONCENTRATES
title_fullStr STUDIES ON THE EXTRACELLULAR CULTIVATION OF AN INTRACELLULAR PARASITE (AVIAN MALARIA) : II. THE EFFECTS OF MALATE AND OF COENZYME A CONCENTRATES
title_full_unstemmed STUDIES ON THE EXTRACELLULAR CULTIVATION OF AN INTRACELLULAR PARASITE (AVIAN MALARIA) : II. THE EFFECTS OF MALATE AND OF COENZYME A CONCENTRATES
title_short STUDIES ON THE EXTRACELLULAR CULTIVATION OF AN INTRACELLULAR PARASITE (AVIAN MALARIA) : II. THE EFFECTS OF MALATE AND OF COENZYME A CONCENTRATES
title_sort studies on the extracellular cultivation of an intracellular parasite (avian malaria) : ii. the effects of malate and of coenzyme a concentrates
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136161/
https://www.ncbi.nlm.nih.gov/pubmed/13000057
work_keys_str_mv AT tragerwilliam studiesontheextracellularcultivationofanintracellularparasiteavianmalariaiitheeffectsofmalateandofcoenzymeaconcentrates

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