THE EFFECT OF X-RADIATION ON THE MULTIPLICATION OF RICKETTSIA MOOSERI IN EMBRYONATE EGGS

The multiplication of Rickettsia mooseri in fertile eggs is speeded up and quantitatively increased by single dose x-radiation given either 24 hours before or 48 hours after inoculation. This effect is noted at all dosage levels studied, ranging from 100 to 1500 r. The rickettsiostatic effects of hi...

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Detalles Bibliográficos
Autores principales: Greiff, Donald, Chiga, Masahiro, Blumenthal, Herman T., Pinkerton, Henry
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136181/
https://www.ncbi.nlm.nih.gov/pubmed/13022869
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author Greiff, Donald
Chiga, Masahiro
Blumenthal, Herman T.
Pinkerton, Henry
author_facet Greiff, Donald
Chiga, Masahiro
Blumenthal, Herman T.
Pinkerton, Henry
author_sort Greiff, Donald
collection PubMed
description The multiplication of Rickettsia mooseri in fertile eggs is speeded up and quantitatively increased by single dose x-radiation given either 24 hours before or 48 hours after inoculation. This effect is noted at all dosage levels studied, ranging from 100 to 1500 r. The rickettsiostatic effects of high incubation temperature (40°C.) and of streptomycin are neutralized by radiation, but the rickettsiostatic actions of PABA, penicillin, and aureomycin are not altered. Possible mechanisms of action and implications of the observed effects are discussed.
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spelling pubmed-21361812008-04-17 THE EFFECT OF X-RADIATION ON THE MULTIPLICATION OF RICKETTSIA MOOSERI IN EMBRYONATE EGGS Greiff, Donald Chiga, Masahiro Blumenthal, Herman T. Pinkerton, Henry J Exp Med Article The multiplication of Rickettsia mooseri in fertile eggs is speeded up and quantitatively increased by single dose x-radiation given either 24 hours before or 48 hours after inoculation. This effect is noted at all dosage levels studied, ranging from 100 to 1500 r. The rickettsiostatic effects of high incubation temperature (40°C.) and of streptomycin are neutralized by radiation, but the rickettsiostatic actions of PABA, penicillin, and aureomycin are not altered. Possible mechanisms of action and implications of the observed effects are discussed. The Rockefeller University Press 1953-01-01 /pmc/articles/PMC2136181/ /pubmed/13022869 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Greiff, Donald
Chiga, Masahiro
Blumenthal, Herman T.
Pinkerton, Henry
THE EFFECT OF X-RADIATION ON THE MULTIPLICATION OF RICKETTSIA MOOSERI IN EMBRYONATE EGGS
title THE EFFECT OF X-RADIATION ON THE MULTIPLICATION OF RICKETTSIA MOOSERI IN EMBRYONATE EGGS
title_full THE EFFECT OF X-RADIATION ON THE MULTIPLICATION OF RICKETTSIA MOOSERI IN EMBRYONATE EGGS
title_fullStr THE EFFECT OF X-RADIATION ON THE MULTIPLICATION OF RICKETTSIA MOOSERI IN EMBRYONATE EGGS
title_full_unstemmed THE EFFECT OF X-RADIATION ON THE MULTIPLICATION OF RICKETTSIA MOOSERI IN EMBRYONATE EGGS
title_short THE EFFECT OF X-RADIATION ON THE MULTIPLICATION OF RICKETTSIA MOOSERI IN EMBRYONATE EGGS
title_sort effect of x-radiation on the multiplication of rickettsia mooseri in embryonate eggs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136181/
https://www.ncbi.nlm.nih.gov/pubmed/13022869
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