THE EXISTENCE OF TWO FORMS OF HYPERTENSIN

Two types of hypertensin have been demonstrated by means of counter-current distribution. The first type is the product of the action of the enzyme, renin, upon its substrate and has been designated hypertensin I. It can be rapidly converted to a second approximately equally pressor compound, hypert...

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Detalles Bibliográficos
Autores principales: Skeggs, Leonard T., Marsh, Walton H., Kahn, Joseph R., Shumway, Norman P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1954
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136205/
https://www.ncbi.nlm.nih.gov/pubmed/13130799
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author Skeggs, Leonard T.
Marsh, Walton H.
Kahn, Joseph R.
Shumway, Norman P.
author_facet Skeggs, Leonard T.
Marsh, Walton H.
Kahn, Joseph R.
Shumway, Norman P.
author_sort Skeggs, Leonard T.
collection PubMed
description Two types of hypertensin have been demonstrated by means of counter-current distribution. The first type is the product of the action of the enzyme, renin, upon its substrate and has been designated hypertensin I. It can be rapidly converted to a second approximately equally pressor compound, hypertensin II, apparently through the action of an enzyme in the plasma which requires halide or nitrate for activation. A highly purified preparation containing horse hypertensins I and II caused an elevation of blood pressure when injected into human beings.
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spelling pubmed-21362052008-04-17 THE EXISTENCE OF TWO FORMS OF HYPERTENSIN Skeggs, Leonard T. Marsh, Walton H. Kahn, Joseph R. Shumway, Norman P. J Exp Med Article Two types of hypertensin have been demonstrated by means of counter-current distribution. The first type is the product of the action of the enzyme, renin, upon its substrate and has been designated hypertensin I. It can be rapidly converted to a second approximately equally pressor compound, hypertensin II, apparently through the action of an enzyme in the plasma which requires halide or nitrate for activation. A highly purified preparation containing horse hypertensins I and II caused an elevation of blood pressure when injected into human beings. The Rockefeller University Press 1954-02-28 /pmc/articles/PMC2136205/ /pubmed/13130799 Text en Copyright © Copyright, 1954, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Skeggs, Leonard T.
Marsh, Walton H.
Kahn, Joseph R.
Shumway, Norman P.
THE EXISTENCE OF TWO FORMS OF HYPERTENSIN
title THE EXISTENCE OF TWO FORMS OF HYPERTENSIN
title_full THE EXISTENCE OF TWO FORMS OF HYPERTENSIN
title_fullStr THE EXISTENCE OF TWO FORMS OF HYPERTENSIN
title_full_unstemmed THE EXISTENCE OF TWO FORMS OF HYPERTENSIN
title_short THE EXISTENCE OF TWO FORMS OF HYPERTENSIN
title_sort existence of two forms of hypertensin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136205/
https://www.ncbi.nlm.nih.gov/pubmed/13130799
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