ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi

We report the identification and characterization of ERS-24 (Endoplasmic Reticulum SNARE of 24 kD), a new mammalian v-SNARE implicated in vesicular transport between the ER and the Golgi. ERS24 is incorporated into 20S docking and fusion particles and disassembles from this complex in an ATP-depende...

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Detalles Bibliográficos
Autores principales: Paek, Inbok, Orci, Lelio, Ravazzola, Mariella, Erdjument-Bromage, Hediye, Amherdt, Mylene, Tempst, Paul, Söllner, Thomas H., Rothman, James E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136225/
https://www.ncbi.nlm.nih.gov/pubmed/9166403
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author Paek, Inbok
Orci, Lelio
Ravazzola, Mariella
Erdjument-Bromage, Hediye
Amherdt, Mylene
Tempst, Paul
Söllner, Thomas H.
Rothman, James E.
author_facet Paek, Inbok
Orci, Lelio
Ravazzola, Mariella
Erdjument-Bromage, Hediye
Amherdt, Mylene
Tempst, Paul
Söllner, Thomas H.
Rothman, James E.
author_sort Paek, Inbok
collection PubMed
description We report the identification and characterization of ERS-24 (Endoplasmic Reticulum SNARE of 24 kD), a new mammalian v-SNARE implicated in vesicular transport between the ER and the Golgi. ERS24 is incorporated into 20S docking and fusion particles and disassembles from this complex in an ATP-dependent manner. ERS-24 has significant sequence homology to Sec22p, a v-SNARE in Saccharomyces cerevisiae required for transport between the ER and the Golgi. ERS-24 is localized to the ER and to the Golgi, and it is enriched in transport vesicles associated with these organelles.
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spelling pubmed-21362252008-05-01 ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi Paek, Inbok Orci, Lelio Ravazzola, Mariella Erdjument-Bromage, Hediye Amherdt, Mylene Tempst, Paul Söllner, Thomas H. Rothman, James E. J Cell Biol Article We report the identification and characterization of ERS-24 (Endoplasmic Reticulum SNARE of 24 kD), a new mammalian v-SNARE implicated in vesicular transport between the ER and the Golgi. ERS24 is incorporated into 20S docking and fusion particles and disassembles from this complex in an ATP-dependent manner. ERS-24 has significant sequence homology to Sec22p, a v-SNARE in Saccharomyces cerevisiae required for transport between the ER and the Golgi. ERS-24 is localized to the ER and to the Golgi, and it is enriched in transport vesicles associated with these organelles. The Rockefeller University Press 1997-06-02 /pmc/articles/PMC2136225/ /pubmed/9166403 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Paek, Inbok
Orci, Lelio
Ravazzola, Mariella
Erdjument-Bromage, Hediye
Amherdt, Mylene
Tempst, Paul
Söllner, Thomas H.
Rothman, James E.
ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi
title ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi
title_full ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi
title_fullStr ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi
title_full_unstemmed ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi
title_short ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi
title_sort ers-24, a mammalian v-snare implicated in vesicle traffic between the er and the golgi
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136225/
https://www.ncbi.nlm.nih.gov/pubmed/9166403
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