STUDIES ON THE ACTIVATION OF SERUM PROTEASE BY AN ANTIGEN-ANTIBODY SYSTEM

The results obtained in this study indicate that serum protease is not activated by either a rabbit or guinea pig antiovalbumin-ovalbumin system, in vitro. A precipitin reaction occurring in the presence of a serum protease precursor of three species (human, rabbit, and guinea pig) failed to activat...

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Detalles Bibliográficos
Autores principales: Jemski, Joseph V., Flick, John A., Stinebring, Warren R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136266/
https://www.ncbi.nlm.nih.gov/pubmed/13052811
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author Jemski, Joseph V.
Flick, John A.
Stinebring, Warren R.
author_facet Jemski, Joseph V.
Flick, John A.
Stinebring, Warren R.
author_sort Jemski, Joseph V.
collection PubMed
description The results obtained in this study indicate that serum protease is not activated by either a rabbit or guinea pig antiovalbumin-ovalbumin system, in vitro. A precipitin reaction occurring in the presence of a serum protease precursor of three species (human, rabbit, and guinea pig) failed to activate the protease precursor. Furthermore, particulate material as preformed precipitates could not be shown to activate the protease of either human or rabbit serum or their euglobulin fractions. The material presented seems to be further evidence against the postulated role of serum protease in immunologic systems.
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spelling pubmed-21362662008-04-17 STUDIES ON THE ACTIVATION OF SERUM PROTEASE BY AN ANTIGEN-ANTIBODY SYSTEM Jemski, Joseph V. Flick, John A. Stinebring, Warren R. J Exp Med Article The results obtained in this study indicate that serum protease is not activated by either a rabbit or guinea pig antiovalbumin-ovalbumin system, in vitro. A precipitin reaction occurring in the presence of a serum protease precursor of three species (human, rabbit, and guinea pig) failed to activate the protease precursor. Furthermore, particulate material as preformed precipitates could not be shown to activate the protease of either human or rabbit serum or their euglobulin fractions. The material presented seems to be further evidence against the postulated role of serum protease in immunologic systems. The Rockefeller University Press 1953-02-28 /pmc/articles/PMC2136266/ /pubmed/13052811 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Jemski, Joseph V.
Flick, John A.
Stinebring, Warren R.
STUDIES ON THE ACTIVATION OF SERUM PROTEASE BY AN ANTIGEN-ANTIBODY SYSTEM
title STUDIES ON THE ACTIVATION OF SERUM PROTEASE BY AN ANTIGEN-ANTIBODY SYSTEM
title_full STUDIES ON THE ACTIVATION OF SERUM PROTEASE BY AN ANTIGEN-ANTIBODY SYSTEM
title_fullStr STUDIES ON THE ACTIVATION OF SERUM PROTEASE BY AN ANTIGEN-ANTIBODY SYSTEM
title_full_unstemmed STUDIES ON THE ACTIVATION OF SERUM PROTEASE BY AN ANTIGEN-ANTIBODY SYSTEM
title_short STUDIES ON THE ACTIVATION OF SERUM PROTEASE BY AN ANTIGEN-ANTIBODY SYSTEM
title_sort studies on the activation of serum protease by an antigen-antibody system
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136266/
https://www.ncbi.nlm.nih.gov/pubmed/13052811
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