EFFECT OF THE COMPOSITION OF THE GASEOUS AND AQUEOUS ENVIRONMENTS ON THE SURVIVAL OF TUBERCLE BACILLI IN VITRO

Tubercle bacilli die much more rapidly under anaerobic than under aerobic conditions. Anaerobically, the rate of death is accelerated by increased CO(2) pressure, and when certain metabolites (lactate for example) are present in the medium. Death of the bacilli under certain conditions of anaerobios...

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Detalles Bibliográficos
Autor principal: Dubos, René J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136267/
https://www.ncbi.nlm.nih.gov/pubmed/13052806
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author Dubos, René J.
author_facet Dubos, René J.
author_sort Dubos, René J.
collection PubMed
description Tubercle bacilli die much more rapidly under anaerobic than under aerobic conditions. Anaerobically, the rate of death is accelerated by increased CO(2) pressure, and when certain metabolites (lactate for example) are present in the medium. Death of the bacilli under certain conditions of anaerobiosis is accompanied by loss of ability to take the acid-fast stain and by progressive cellular disintegration. These findings are discussed in relation to (a) the glycolytic equipment of tubercle bacilli, (b) their fate in tuberculous lesions.
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spelling pubmed-21362672008-04-17 EFFECT OF THE COMPOSITION OF THE GASEOUS AND AQUEOUS ENVIRONMENTS ON THE SURVIVAL OF TUBERCLE BACILLI IN VITRO Dubos, René J. J Exp Med Article Tubercle bacilli die much more rapidly under anaerobic than under aerobic conditions. Anaerobically, the rate of death is accelerated by increased CO(2) pressure, and when certain metabolites (lactate for example) are present in the medium. Death of the bacilli under certain conditions of anaerobiosis is accompanied by loss of ability to take the acid-fast stain and by progressive cellular disintegration. These findings are discussed in relation to (a) the glycolytic equipment of tubercle bacilli, (b) their fate in tuberculous lesions. The Rockefeller University Press 1953-02-28 /pmc/articles/PMC2136267/ /pubmed/13052806 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Dubos, René J.
EFFECT OF THE COMPOSITION OF THE GASEOUS AND AQUEOUS ENVIRONMENTS ON THE SURVIVAL OF TUBERCLE BACILLI IN VITRO
title EFFECT OF THE COMPOSITION OF THE GASEOUS AND AQUEOUS ENVIRONMENTS ON THE SURVIVAL OF TUBERCLE BACILLI IN VITRO
title_full EFFECT OF THE COMPOSITION OF THE GASEOUS AND AQUEOUS ENVIRONMENTS ON THE SURVIVAL OF TUBERCLE BACILLI IN VITRO
title_fullStr EFFECT OF THE COMPOSITION OF THE GASEOUS AND AQUEOUS ENVIRONMENTS ON THE SURVIVAL OF TUBERCLE BACILLI IN VITRO
title_full_unstemmed EFFECT OF THE COMPOSITION OF THE GASEOUS AND AQUEOUS ENVIRONMENTS ON THE SURVIVAL OF TUBERCLE BACILLI IN VITRO
title_short EFFECT OF THE COMPOSITION OF THE GASEOUS AND AQUEOUS ENVIRONMENTS ON THE SURVIVAL OF TUBERCLE BACILLI IN VITRO
title_sort effect of the composition of the gaseous and aqueous environments on the survival of tubercle bacilli in vitro
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136267/
https://www.ncbi.nlm.nih.gov/pubmed/13052806
work_keys_str_mv AT dubosrenej effectofthecompositionofthegaseousandaqueousenvironmentsonthesurvivaloftuberclebacilliinvitro

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