A HISTOLOGICAL STUDY OF INFECTIOUS CANINE HEPATITIS BY MEANS OF FLUORESCENT ANTIBODY

A study of experimental infectious canine hepatitis in dogs by means of specific fluorescent antibody indicates that the intranuclear inclusions of this disease contain high concentrations of viral antigen. The increase in virus in the nuclei, as indicated by the accumulation of specific antigenic m...

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Detalles Bibliográficos
Autores principales: Coffin, David L., Coons, Albert H., Cabasso, Victor J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136277/
https://www.ncbi.nlm.nih.gov/pubmed/13069646
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author Coffin, David L.
Coons, Albert H.
Cabasso, Victor J.
author_facet Coffin, David L.
Coons, Albert H.
Cabasso, Victor J.
author_sort Coffin, David L.
collection PubMed
description A study of experimental infectious canine hepatitis in dogs by means of specific fluorescent antibody indicates that the intranuclear inclusions of this disease contain high concentrations of viral antigen. The increase in virus in the nuclei, as indicated by the accumulation of specific antigenic material, begins on the nuclear membrane and spreads from there to the interior of the nucleus, with the gradual formation of larger granules. Subsequently there appear the homogeneous inclusion bodies characteristic of this infection.
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spelling pubmed-21362772008-04-17 A HISTOLOGICAL STUDY OF INFECTIOUS CANINE HEPATITIS BY MEANS OF FLUORESCENT ANTIBODY Coffin, David L. Coons, Albert H. Cabasso, Victor J. J Exp Med Article A study of experimental infectious canine hepatitis in dogs by means of specific fluorescent antibody indicates that the intranuclear inclusions of this disease contain high concentrations of viral antigen. The increase in virus in the nuclei, as indicated by the accumulation of specific antigenic material, begins on the nuclear membrane and spreads from there to the interior of the nucleus, with the gradual formation of larger granules. Subsequently there appear the homogeneous inclusion bodies characteristic of this infection. The Rockefeller University Press 1953-07-01 /pmc/articles/PMC2136277/ /pubmed/13069646 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Coffin, David L.
Coons, Albert H.
Cabasso, Victor J.
A HISTOLOGICAL STUDY OF INFECTIOUS CANINE HEPATITIS BY MEANS OF FLUORESCENT ANTIBODY
title A HISTOLOGICAL STUDY OF INFECTIOUS CANINE HEPATITIS BY MEANS OF FLUORESCENT ANTIBODY
title_full A HISTOLOGICAL STUDY OF INFECTIOUS CANINE HEPATITIS BY MEANS OF FLUORESCENT ANTIBODY
title_fullStr A HISTOLOGICAL STUDY OF INFECTIOUS CANINE HEPATITIS BY MEANS OF FLUORESCENT ANTIBODY
title_full_unstemmed A HISTOLOGICAL STUDY OF INFECTIOUS CANINE HEPATITIS BY MEANS OF FLUORESCENT ANTIBODY
title_short A HISTOLOGICAL STUDY OF INFECTIOUS CANINE HEPATITIS BY MEANS OF FLUORESCENT ANTIBODY
title_sort histological study of infectious canine hepatitis by means of fluorescent antibody
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136277/
https://www.ncbi.nlm.nih.gov/pubmed/13069646
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