INDUCED MALIGNANCY IN CELLS FROM RAT MYOCARDIUM SUBJECTED TO INTERMITTENT ANAEROBIOSIS DURING LONG PROPAGATION IN VITRO

In two strains of fibroblasts originating from fragments of myocardium from a 5 day old rat of the Slonaker-Addis strain, a strain known to develop tumors but rarely, abnormal morphologic alterations took place which eventuated in neoplastic changes. This happened only after repeated exposure of the...

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Detalles Bibliográficos
Autores principales: Goldblatt, Harry, Cameron, Gladys
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136288/
https://www.ncbi.nlm.nih.gov/pubmed/13052818
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author Goldblatt, Harry
Cameron, Gladys
author_facet Goldblatt, Harry
Cameron, Gladys
author_sort Goldblatt, Harry
collection PubMed
description In two strains of fibroblasts originating from fragments of myocardium from a 5 day old rat of the Slonaker-Addis strain, a strain known to develop tumors but rarely, abnormal morphologic alterations took place which eventuated in neoplastic changes. This happened only after repeated exposure of the cultures to an atmosphere of nitrogen (anaerobiosis) and did not occur in the control cultures of fibroblasts originating from the same rat heart, and grown continuously throughout the same period (2 ½ years) without exposure to nitrogen.
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spelling pubmed-21362882008-04-17 INDUCED MALIGNANCY IN CELLS FROM RAT MYOCARDIUM SUBJECTED TO INTERMITTENT ANAEROBIOSIS DURING LONG PROPAGATION IN VITRO Goldblatt, Harry Cameron, Gladys J Exp Med Article In two strains of fibroblasts originating from fragments of myocardium from a 5 day old rat of the Slonaker-Addis strain, a strain known to develop tumors but rarely, abnormal morphologic alterations took place which eventuated in neoplastic changes. This happened only after repeated exposure of the cultures to an atmosphere of nitrogen (anaerobiosis) and did not occur in the control cultures of fibroblasts originating from the same rat heart, and grown continuously throughout the same period (2 ½ years) without exposure to nitrogen. The Rockefeller University Press 1953-03-31 /pmc/articles/PMC2136288/ /pubmed/13052818 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Goldblatt, Harry
Cameron, Gladys
INDUCED MALIGNANCY IN CELLS FROM RAT MYOCARDIUM SUBJECTED TO INTERMITTENT ANAEROBIOSIS DURING LONG PROPAGATION IN VITRO
title INDUCED MALIGNANCY IN CELLS FROM RAT MYOCARDIUM SUBJECTED TO INTERMITTENT ANAEROBIOSIS DURING LONG PROPAGATION IN VITRO
title_full INDUCED MALIGNANCY IN CELLS FROM RAT MYOCARDIUM SUBJECTED TO INTERMITTENT ANAEROBIOSIS DURING LONG PROPAGATION IN VITRO
title_fullStr INDUCED MALIGNANCY IN CELLS FROM RAT MYOCARDIUM SUBJECTED TO INTERMITTENT ANAEROBIOSIS DURING LONG PROPAGATION IN VITRO
title_full_unstemmed INDUCED MALIGNANCY IN CELLS FROM RAT MYOCARDIUM SUBJECTED TO INTERMITTENT ANAEROBIOSIS DURING LONG PROPAGATION IN VITRO
title_short INDUCED MALIGNANCY IN CELLS FROM RAT MYOCARDIUM SUBJECTED TO INTERMITTENT ANAEROBIOSIS DURING LONG PROPAGATION IN VITRO
title_sort induced malignancy in cells from rat myocardium subjected to intermittent anaerobiosis during long propagation in vitro
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136288/
https://www.ncbi.nlm.nih.gov/pubmed/13052818
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AT camerongladys inducedmalignancyincellsfromratmyocardiumsubjectedtointermittentanaerobiosisduringlongpropagationinvitro

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