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AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : II. EFFECT OF HELENINE UPON INFECTION IN MICE WITH SEMLIKI FOREST VIRUS
Helenine exerts a therapeutic effect against Semliki Forest virus infections of mice. Cures, that is to say the survival of treated animals, were more frequently observed in Semliki Forest virus infections than they were in SK virus infections. It is believed that this difference in end-result proba...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1953
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136304/ https://www.ncbi.nlm.nih.gov/pubmed/13052823 |
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author | Shope, Richard E. |
author_facet | Shope, Richard E. |
author_sort | Shope, Richard E. |
collection | PubMed |
description | Helenine exerts a therapeutic effect against Semliki Forest virus infections of mice. Cures, that is to say the survival of treated animals, were more frequently observed in Semliki Forest virus infections than they were in SK virus infections. It is believed that this difference in end-result probably represented only a quantitative difference in the therapeutic effect of helenine against these two viruses and not a qualitative difference in its mechanism of therapeutic action. The findings reported in this paper with regard to the treatment of Semliki Forest virus infections with helenine parallel very closely those described in an accompanying paper which deals with the action of helenine on SK. virus infections. |
format | Text |
id | pubmed-2136304 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1953 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21363042008-04-17 AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : II. EFFECT OF HELENINE UPON INFECTION IN MICE WITH SEMLIKI FOREST VIRUS Shope, Richard E. J Exp Med Article Helenine exerts a therapeutic effect against Semliki Forest virus infections of mice. Cures, that is to say the survival of treated animals, were more frequently observed in Semliki Forest virus infections than they were in SK virus infections. It is believed that this difference in end-result probably represented only a quantitative difference in the therapeutic effect of helenine against these two viruses and not a qualitative difference in its mechanism of therapeutic action. The findings reported in this paper with regard to the treatment of Semliki Forest virus infections with helenine parallel very closely those described in an accompanying paper which deals with the action of helenine on SK. virus infections. The Rockefeller University Press 1953-05-01 /pmc/articles/PMC2136304/ /pubmed/13052823 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Shope, Richard E. AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : II. EFFECT OF HELENINE UPON INFECTION IN MICE WITH SEMLIKI FOREST VIRUS |
title | AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : II. EFFECT OF HELENINE UPON INFECTION IN MICE WITH SEMLIKI FOREST VIRUS |
title_full | AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : II. EFFECT OF HELENINE UPON INFECTION IN MICE WITH SEMLIKI FOREST VIRUS |
title_fullStr | AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : II. EFFECT OF HELENINE UPON INFECTION IN MICE WITH SEMLIKI FOREST VIRUS |
title_full_unstemmed | AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : II. EFFECT OF HELENINE UPON INFECTION IN MICE WITH SEMLIKI FOREST VIRUS |
title_short | AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : II. EFFECT OF HELENINE UPON INFECTION IN MICE WITH SEMLIKI FOREST VIRUS |
title_sort | antiviral substance from penicillium funiculosum : ii. effect of helenine upon infection in mice with semliki forest virus |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136304/ https://www.ncbi.nlm.nih.gov/pubmed/13052823 |
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