THE OCCURRENCE OF CHANGES RESEMBLING THE INFLAMMATORY IN SKIN INJURED AND INCUBATED AFTER EXCISION

Observations are reported on the changes which occurred in excised rabbit and human skin after mild trauma and incubation at body temperature. These changes resembled those of chronic inflammation, in that perivascular and diffuse infiltration by histiocytes occurred in the corium and subcutaneous t...

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Detalles Bibliográficos
Autores principales: Cooke, Jean V., Goldring, David, Kahn, Lawrence I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136305/
https://www.ncbi.nlm.nih.gov/pubmed/13052825
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author Cooke, Jean V.
Goldring, David
Kahn, Lawrence I.
author_facet Cooke, Jean V.
Goldring, David
Kahn, Lawrence I.
author_sort Cooke, Jean V.
collection PubMed
description Observations are reported on the changes which occurred in excised rabbit and human skin after mild trauma and incubation at body temperature. These changes resembled those of chronic inflammation, in that perivascular and diffuse infiltration by histiocytes occurred in the corium and subcutaneous tissue, but they developed within a few hours. The experiments have shown that even after removal from the body certain tissue elements may retain the ability to react with proliferative changes in response to tissue injury if kept under artificially simulated physiological conditions. The possible significance of these changes in relation to the inflammatory process is discussed.
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spelling pubmed-21363052008-04-17 THE OCCURRENCE OF CHANGES RESEMBLING THE INFLAMMATORY IN SKIN INJURED AND INCUBATED AFTER EXCISION Cooke, Jean V. Goldring, David Kahn, Lawrence I. J Exp Med Article Observations are reported on the changes which occurred in excised rabbit and human skin after mild trauma and incubation at body temperature. These changes resembled those of chronic inflammation, in that perivascular and diffuse infiltration by histiocytes occurred in the corium and subcutaneous tissue, but they developed within a few hours. The experiments have shown that even after removal from the body certain tissue elements may retain the ability to react with proliferative changes in response to tissue injury if kept under artificially simulated physiological conditions. The possible significance of these changes in relation to the inflammatory process is discussed. The Rockefeller University Press 1953-05-01 /pmc/articles/PMC2136305/ /pubmed/13052825 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Cooke, Jean V.
Goldring, David
Kahn, Lawrence I.
THE OCCURRENCE OF CHANGES RESEMBLING THE INFLAMMATORY IN SKIN INJURED AND INCUBATED AFTER EXCISION
title THE OCCURRENCE OF CHANGES RESEMBLING THE INFLAMMATORY IN SKIN INJURED AND INCUBATED AFTER EXCISION
title_full THE OCCURRENCE OF CHANGES RESEMBLING THE INFLAMMATORY IN SKIN INJURED AND INCUBATED AFTER EXCISION
title_fullStr THE OCCURRENCE OF CHANGES RESEMBLING THE INFLAMMATORY IN SKIN INJURED AND INCUBATED AFTER EXCISION
title_full_unstemmed THE OCCURRENCE OF CHANGES RESEMBLING THE INFLAMMATORY IN SKIN INJURED AND INCUBATED AFTER EXCISION
title_short THE OCCURRENCE OF CHANGES RESEMBLING THE INFLAMMATORY IN SKIN INJURED AND INCUBATED AFTER EXCISION
title_sort occurrence of changes resembling the inflammatory in skin injured and incubated after excision
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136305/
https://www.ncbi.nlm.nih.gov/pubmed/13052825
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