INHIBITION OF THEILER'S ENCEPHALOMYELITIS VIRUS (GDVII STRAIN) OF MICE BY AN INTESTINAL MUCOPOLYSACCHARIDE : II. PURIFICATION AND PROPERTIES OF THE MUCOPOLYSACCHARIDE

A mucopolysaccharide inhibitor of Theiler's GDVII virus has been purified from intestinal tissue of adult mice. The purified material has been shown to consist chiefly of carbohydrate. Following acid hydrolysis of the inhibitor, several amino adds were found to be present. The carbohydrate comp...

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Detalles Bibliográficos
Autores principales: Mandel, Benjamin, Racker, Efraim
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136332/
https://www.ncbi.nlm.nih.gov/pubmed/13109098
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author Mandel, Benjamin
Racker, Efraim
author_facet Mandel, Benjamin
Racker, Efraim
author_sort Mandel, Benjamin
collection PubMed
description A mucopolysaccharide inhibitor of Theiler's GDVII virus has been purified from intestinal tissue of adult mice. The purified material has been shown to consist chiefly of carbohydrate. Following acid hydrolysis of the inhibitor, several amino adds were found to be present. The carbohydrate components shown to be present thus far are galactose, hexosamine, N-acetylhexosamine, methylpentose, hexurornic acid; an indication has been obtained that sedoheptulose is also present. The available evidence strongly suggests that this mucopolysaccharide, and not some other substance present in minute amounts, is the inhibitor of the GDVII virus.
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spelling pubmed-21363322008-04-17 INHIBITION OF THEILER'S ENCEPHALOMYELITIS VIRUS (GDVII STRAIN) OF MICE BY AN INTESTINAL MUCOPOLYSACCHARIDE : II. PURIFICATION AND PROPERTIES OF THE MUCOPOLYSACCHARIDE Mandel, Benjamin Racker, Efraim J Exp Med Article A mucopolysaccharide inhibitor of Theiler's GDVII virus has been purified from intestinal tissue of adult mice. The purified material has been shown to consist chiefly of carbohydrate. Following acid hydrolysis of the inhibitor, several amino adds were found to be present. The carbohydrate components shown to be present thus far are galactose, hexosamine, N-acetylhexosamine, methylpentose, hexurornic acid; an indication has been obtained that sedoheptulose is also present. The available evidence strongly suggests that this mucopolysaccharide, and not some other substance present in minute amounts, is the inhibitor of the GDVII virus. The Rockefeller University Press 1953-10-31 /pmc/articles/PMC2136332/ /pubmed/13109098 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Mandel, Benjamin
Racker, Efraim
INHIBITION OF THEILER'S ENCEPHALOMYELITIS VIRUS (GDVII STRAIN) OF MICE BY AN INTESTINAL MUCOPOLYSACCHARIDE : II. PURIFICATION AND PROPERTIES OF THE MUCOPOLYSACCHARIDE
title INHIBITION OF THEILER'S ENCEPHALOMYELITIS VIRUS (GDVII STRAIN) OF MICE BY AN INTESTINAL MUCOPOLYSACCHARIDE : II. PURIFICATION AND PROPERTIES OF THE MUCOPOLYSACCHARIDE
title_full INHIBITION OF THEILER'S ENCEPHALOMYELITIS VIRUS (GDVII STRAIN) OF MICE BY AN INTESTINAL MUCOPOLYSACCHARIDE : II. PURIFICATION AND PROPERTIES OF THE MUCOPOLYSACCHARIDE
title_fullStr INHIBITION OF THEILER'S ENCEPHALOMYELITIS VIRUS (GDVII STRAIN) OF MICE BY AN INTESTINAL MUCOPOLYSACCHARIDE : II. PURIFICATION AND PROPERTIES OF THE MUCOPOLYSACCHARIDE
title_full_unstemmed INHIBITION OF THEILER'S ENCEPHALOMYELITIS VIRUS (GDVII STRAIN) OF MICE BY AN INTESTINAL MUCOPOLYSACCHARIDE : II. PURIFICATION AND PROPERTIES OF THE MUCOPOLYSACCHARIDE
title_short INHIBITION OF THEILER'S ENCEPHALOMYELITIS VIRUS (GDVII STRAIN) OF MICE BY AN INTESTINAL MUCOPOLYSACCHARIDE : II. PURIFICATION AND PROPERTIES OF THE MUCOPOLYSACCHARIDE
title_sort inhibition of theiler's encephalomyelitis virus (gdvii strain) of mice by an intestinal mucopolysaccharide : ii. purification and properties of the mucopolysaccharide
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136332/
https://www.ncbi.nlm.nih.gov/pubmed/13109098
work_keys_str_mv AT mandelbenjamin inhibitionoftheilersencephalomyelitisvirusgdviistrainofmicebyanintestinalmucopolysaccharideiipurificationandpropertiesofthemucopolysaccharide
AT rackerefraim inhibitionoftheilersencephalomyelitisvirusgdviistrainofmicebyanintestinalmucopolysaccharideiipurificationandpropertiesofthemucopolysaccharide

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