THE ESTIMATION OF CIRCULATING ANTIBODY-ANTIGEN COMPLEX

Immune sera were subjected to treatment with alkali in the cold to cause dissociation of antigen-antibody complexes. Precipitates and a capacity to fix complement developed in some of these sera subsequent to such treatment. The specific immunologic nature of these phenomena and their observation in...

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Detalles Bibliográficos
Autores principales: Sternberger, L. A., Maltaner, Frank, DeWeerdt, Jacob
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136334/
https://www.ncbi.nlm.nih.gov/pubmed/13109102
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author Sternberger, L. A.
Maltaner, Frank
DeWeerdt, Jacob
author_facet Sternberger, L. A.
Maltaner, Frank
DeWeerdt, Jacob
author_sort Sternberger, L. A.
collection PubMed
description Immune sera were subjected to treatment with alkali in the cold to cause dissociation of antigen-antibody complexes. Precipitates and a capacity to fix complement developed in some of these sera subsequent to such treatment. The specific immunologic nature of these phenomena and their observation in relation to disappearance of free antigen and appearance of free antibody in circulation are discussed. The phenomena observed appear to be consistent with the assumption that a circulating antibody-antigen complex is revealed as a result of treatment.
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spelling pubmed-21363342008-04-17 THE ESTIMATION OF CIRCULATING ANTIBODY-ANTIGEN COMPLEX Sternberger, L. A. Maltaner, Frank DeWeerdt, Jacob J Exp Med Article Immune sera were subjected to treatment with alkali in the cold to cause dissociation of antigen-antibody complexes. Precipitates and a capacity to fix complement developed in some of these sera subsequent to such treatment. The specific immunologic nature of these phenomena and their observation in relation to disappearance of free antigen and appearance of free antibody in circulation are discussed. The phenomena observed appear to be consistent with the assumption that a circulating antibody-antigen complex is revealed as a result of treatment. The Rockefeller University Press 1953-10-31 /pmc/articles/PMC2136334/ /pubmed/13109102 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Sternberger, L. A.
Maltaner, Frank
DeWeerdt, Jacob
THE ESTIMATION OF CIRCULATING ANTIBODY-ANTIGEN COMPLEX
title THE ESTIMATION OF CIRCULATING ANTIBODY-ANTIGEN COMPLEX
title_full THE ESTIMATION OF CIRCULATING ANTIBODY-ANTIGEN COMPLEX
title_fullStr THE ESTIMATION OF CIRCULATING ANTIBODY-ANTIGEN COMPLEX
title_full_unstemmed THE ESTIMATION OF CIRCULATING ANTIBODY-ANTIGEN COMPLEX
title_short THE ESTIMATION OF CIRCULATING ANTIBODY-ANTIGEN COMPLEX
title_sort estimation of circulating antibody-antigen complex
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136334/
https://www.ncbi.nlm.nih.gov/pubmed/13109102
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