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STRUCTURE AND DEVELOPMENT OF VIRUSES OBSERVED IN THE ELECTRON MICROSCOPE : II. VACCINIA AND FOWL POX VIRUSES
Vaccinia and fowl pox viruses were visualized by the electron microscope in sections of infected chorioallantoic membrane of chicken embryos. The viruses were of similar structure and size, averaging 200 x 300 mµ with considerable individual variation. Intracytoplasmic viral particles contained a de...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1954
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136374/ https://www.ncbi.nlm.nih.gov/pubmed/13192254 |
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author | Morgan, Councilman Ellison, Solon A. Rose, Harry M. Moore, Dan H. |
author_facet | Morgan, Councilman Ellison, Solon A. Rose, Harry M. Moore, Dan H. |
author_sort | Morgan, Councilman |
collection | PubMed |
description | Vaccinia and fowl pox viruses were visualized by the electron microscope in sections of infected chorioallantoic membrane of chicken embryos. The viruses were of similar structure and size, averaging 200 x 300 mµ with considerable individual variation. Intracytoplasmic viral particles contained a dense, nucleus-like body (nucleoid) separated from granular material (viroplasm) by a zone of lesser density. They were enclosed by a single membrane. Near the surface of the host cell and in the extracellular space the particles consisted of a central body of variable shape and density enclosed by a double membrane. The initial sites of development were confined to the cytoplasm of the host cell. Before release from the host cell the viral nucleoids appeared to enlarge and to occupy a central position within the particle, which became enclosed by a double limiting membrane. The brick-shaped forms found after removal of the embedding plastic from thick sections indicated that drying caused characteristic distortion of certain viral particles. |
format | Text |
id | pubmed-2136374 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1954 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21363742008-04-17 STRUCTURE AND DEVELOPMENT OF VIRUSES OBSERVED IN THE ELECTRON MICROSCOPE : II. VACCINIA AND FOWL POX VIRUSES Morgan, Councilman Ellison, Solon A. Rose, Harry M. Moore, Dan H. J Exp Med Article Vaccinia and fowl pox viruses were visualized by the electron microscope in sections of infected chorioallantoic membrane of chicken embryos. The viruses were of similar structure and size, averaging 200 x 300 mµ with considerable individual variation. Intracytoplasmic viral particles contained a dense, nucleus-like body (nucleoid) separated from granular material (viroplasm) by a zone of lesser density. They were enclosed by a single membrane. Near the surface of the host cell and in the extracellular space the particles consisted of a central body of variable shape and density enclosed by a double membrane. The initial sites of development were confined to the cytoplasm of the host cell. Before release from the host cell the viral nucleoids appeared to enlarge and to occupy a central position within the particle, which became enclosed by a double limiting membrane. The brick-shaped forms found after removal of the embedding plastic from thick sections indicated that drying caused characteristic distortion of certain viral particles. The Rockefeller University Press 1954-09-01 /pmc/articles/PMC2136374/ /pubmed/13192254 Text en Copyright © Copyright, 1954, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Morgan, Councilman Ellison, Solon A. Rose, Harry M. Moore, Dan H. STRUCTURE AND DEVELOPMENT OF VIRUSES OBSERVED IN THE ELECTRON MICROSCOPE : II. VACCINIA AND FOWL POX VIRUSES |
title | STRUCTURE AND DEVELOPMENT OF VIRUSES OBSERVED IN THE ELECTRON MICROSCOPE : II. VACCINIA AND FOWL POX VIRUSES |
title_full | STRUCTURE AND DEVELOPMENT OF VIRUSES OBSERVED IN THE ELECTRON MICROSCOPE : II. VACCINIA AND FOWL POX VIRUSES |
title_fullStr | STRUCTURE AND DEVELOPMENT OF VIRUSES OBSERVED IN THE ELECTRON MICROSCOPE : II. VACCINIA AND FOWL POX VIRUSES |
title_full_unstemmed | STRUCTURE AND DEVELOPMENT OF VIRUSES OBSERVED IN THE ELECTRON MICROSCOPE : II. VACCINIA AND FOWL POX VIRUSES |
title_short | STRUCTURE AND DEVELOPMENT OF VIRUSES OBSERVED IN THE ELECTRON MICROSCOPE : II. VACCINIA AND FOWL POX VIRUSES |
title_sort | structure and development of viruses observed in the electron microscope : ii. vaccinia and fowl pox viruses |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136374/ https://www.ncbi.nlm.nih.gov/pubmed/13192254 |
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