THE INFLUENCE OF ANTICOAGULANTS ON THE FORMATION AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROSIS

The prolonged administration of either heparin or dicoumerol has been demonstrated to be effective in retarding the formation of atheromata in the cholesterol-fed chick. This beneficial action is possibly produced as a result of a demonstrated antihypercholesteremic action exerted by these anticoagu...

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Detalles Bibliográficos
Autores principales: Horita, Akira, Loomis, T. A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1954
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136380/
https://www.ncbi.nlm.nih.gov/pubmed/13201715
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author Horita, Akira
Loomis, T. A.
author_facet Horita, Akira
Loomis, T. A.
author_sort Horita, Akira
collection PubMed
description The prolonged administration of either heparin or dicoumerol has been demonstrated to be effective in retarding the formation of atheromata in the cholesterol-fed chick. This beneficial action is possibly produced as a result of a demonstrated antihypercholesteremic action exerted by these anticoagulants. Heparin is ineffective in preventing the marked turbidity of sera from cholesterol-fed chickens. After the formation of atherosclerosis in the chick neither heparin nor dicoumerol is effective in hastening the regression of this condition. The serum lipid picture as well as the degree of atheroma of the various groups in the regression experiments is unaffected by the anticoagulants.
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spelling pubmed-21363802008-04-17 THE INFLUENCE OF ANTICOAGULANTS ON THE FORMATION AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROSIS Horita, Akira Loomis, T. A. J Exp Med Article The prolonged administration of either heparin or dicoumerol has been demonstrated to be effective in retarding the formation of atheromata in the cholesterol-fed chick. This beneficial action is possibly produced as a result of a demonstrated antihypercholesteremic action exerted by these anticoagulants. Heparin is ineffective in preventing the marked turbidity of sera from cholesterol-fed chickens. After the formation of atherosclerosis in the chick neither heparin nor dicoumerol is effective in hastening the regression of this condition. The serum lipid picture as well as the degree of atheroma of the various groups in the regression experiments is unaffected by the anticoagulants. The Rockefeller University Press 1954-09-30 /pmc/articles/PMC2136380/ /pubmed/13201715 Text en Copyright © Copyright, 1954, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Horita, Akira
Loomis, T. A.
THE INFLUENCE OF ANTICOAGULANTS ON THE FORMATION AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROSIS
title THE INFLUENCE OF ANTICOAGULANTS ON THE FORMATION AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROSIS
title_full THE INFLUENCE OF ANTICOAGULANTS ON THE FORMATION AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROSIS
title_fullStr THE INFLUENCE OF ANTICOAGULANTS ON THE FORMATION AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROSIS
title_full_unstemmed THE INFLUENCE OF ANTICOAGULANTS ON THE FORMATION AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROSIS
title_short THE INFLUENCE OF ANTICOAGULANTS ON THE FORMATION AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROSIS
title_sort influence of anticoagulants on the formation and regression of experimental atherosclerosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136380/
https://www.ncbi.nlm.nih.gov/pubmed/13201715
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