Cargando…

THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY

Evidence has been presented: (1) that macrophages from experimentally produced inflammatory exudates are capable of phagocyting fully encapsulated Type I pneumococci and group A Friedländer's bacilli in the absence of antibody, (2) that the principal mechanisms involved are those of surface pha...

Descripción completa

Detalles Bibliográficos
Autores principales: Sawyer, William D., Smith, Mary Ruth, Wood, W. Barry
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1954
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136383/
https://www.ncbi.nlm.nih.gov/pubmed/13201718
_version_ 1782143114469703680
author Sawyer, William D.
Smith, Mary Ruth
Wood, W. Barry
author_facet Sawyer, William D.
Smith, Mary Ruth
Wood, W. Barry
author_sort Sawyer, William D.
collection PubMed
description Evidence has been presented: (1) that macrophages from experimentally produced inflammatory exudates are capable of phagocyting fully encapsulated Type I pneumococci and group A Friedländer's bacilli in the absence of antibody, (2) that the principal mechanisms involved are those of surface phagocytosis, and (3) that the majority of pneumococci ingested by macrophages in antibody-free preparations are ultimately destroyed. The relationship of these phenomena to the mechanism of recovery in pneumococcal and Friedländer's bacillus infections has been briefly discussed.
format Text
id pubmed-2136383
institution National Center for Biotechnology Information
language English
publishDate 1954
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21363832008-04-17 THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY Sawyer, William D. Smith, Mary Ruth Wood, W. Barry J Exp Med Article Evidence has been presented: (1) that macrophages from experimentally produced inflammatory exudates are capable of phagocyting fully encapsulated Type I pneumococci and group A Friedländer's bacilli in the absence of antibody, (2) that the principal mechanisms involved are those of surface phagocytosis, and (3) that the majority of pneumococci ingested by macrophages in antibody-free preparations are ultimately destroyed. The relationship of these phenomena to the mechanism of recovery in pneumococcal and Friedländer's bacillus infections has been briefly discussed. The Rockefeller University Press 1954-09-30 /pmc/articles/PMC2136383/ /pubmed/13201718 Text en Copyright © Copyright, 1954, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Sawyer, William D.
Smith, Mary Ruth
Wood, W. Barry
THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY
title THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY
title_full THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY
title_fullStr THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY
title_full_unstemmed THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY
title_short THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY
title_sort mechanisms by which macrophages phagocyte encapsulated bacteria in the absence of antibody
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136383/
https://www.ncbi.nlm.nih.gov/pubmed/13201718
work_keys_str_mv AT sawyerwilliamd themechanismsbywhichmacrophagesphagocyteencapsulatedbacteriaintheabsenceofantibody
AT smithmaryruth themechanismsbywhichmacrophagesphagocyteencapsulatedbacteriaintheabsenceofantibody
AT woodwbarry themechanismsbywhichmacrophagesphagocyteencapsulatedbacteriaintheabsenceofantibody
AT sawyerwilliamd mechanismsbywhichmacrophagesphagocyteencapsulatedbacteriaintheabsenceofantibody
AT smithmaryruth mechanismsbywhichmacrophagesphagocyteencapsulatedbacteriaintheabsenceofantibody
AT woodwbarry mechanismsbywhichmacrophagesphagocyteencapsulatedbacteriaintheabsenceofantibody