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THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY
Evidence has been presented: (1) that macrophages from experimentally produced inflammatory exudates are capable of phagocyting fully encapsulated Type I pneumococci and group A Friedländer's bacilli in the absence of antibody, (2) that the principal mechanisms involved are those of surface pha...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1954
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136383/ https://www.ncbi.nlm.nih.gov/pubmed/13201718 |
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author | Sawyer, William D. Smith, Mary Ruth Wood, W. Barry |
author_facet | Sawyer, William D. Smith, Mary Ruth Wood, W. Barry |
author_sort | Sawyer, William D. |
collection | PubMed |
description | Evidence has been presented: (1) that macrophages from experimentally produced inflammatory exudates are capable of phagocyting fully encapsulated Type I pneumococci and group A Friedländer's bacilli in the absence of antibody, (2) that the principal mechanisms involved are those of surface phagocytosis, and (3) that the majority of pneumococci ingested by macrophages in antibody-free preparations are ultimately destroyed. The relationship of these phenomena to the mechanism of recovery in pneumococcal and Friedländer's bacillus infections has been briefly discussed. |
format | Text |
id | pubmed-2136383 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1954 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21363832008-04-17 THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY Sawyer, William D. Smith, Mary Ruth Wood, W. Barry J Exp Med Article Evidence has been presented: (1) that macrophages from experimentally produced inflammatory exudates are capable of phagocyting fully encapsulated Type I pneumococci and group A Friedländer's bacilli in the absence of antibody, (2) that the principal mechanisms involved are those of surface phagocytosis, and (3) that the majority of pneumococci ingested by macrophages in antibody-free preparations are ultimately destroyed. The relationship of these phenomena to the mechanism of recovery in pneumococcal and Friedländer's bacillus infections has been briefly discussed. The Rockefeller University Press 1954-09-30 /pmc/articles/PMC2136383/ /pubmed/13201718 Text en Copyright © Copyright, 1954, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Sawyer, William D. Smith, Mary Ruth Wood, W. Barry THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY |
title | THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY |
title_full | THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY |
title_fullStr | THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY |
title_full_unstemmed | THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY |
title_short | THE MECHANISMS BY WHICH MACROPHAGES PHAGOCYTE ENCAPSULATED BACTERIA IN THE ABSENCE OF ANTIBODY |
title_sort | mechanisms by which macrophages phagocyte encapsulated bacteria in the absence of antibody |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136383/ https://www.ncbi.nlm.nih.gov/pubmed/13201718 |
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