THE NATURE OF PROPHAGE IN LYSOGENIC BACILLUS MEGATHERIUM

1. By complement-fixation tests it has been shown that the lysogenic and sensitive strains of B. megatherium share one or more antigenic components which are serologically related but not identical. 2. Bacilli of the lysogenic strain of B. megatherium, when grown under conditions such that little ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Miller, Elizabeth M., Goebel, Walther F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1954
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136394/
https://www.ncbi.nlm.nih.gov/pubmed/13211912
_version_ 1782143116991528960
author Miller, Elizabeth M.
Goebel, Walther F.
author_facet Miller, Elizabeth M.
Goebel, Walther F.
author_sort Miller, Elizabeth M.
collection PubMed
description 1. By complement-fixation tests it has been shown that the lysogenic and sensitive strains of B. megatherium share one or more antigenic components which are serologically related but not identical. 2. Bacilli of the lysogenic strain of B. megatherium, when grown under conditions such that little extracellular phage is produced, fail to evoke antibodies in rabbits which react either in complement-fixation or neutralization tests with purified megatherium T phage. From this it must be concluded either that prophage is not antigenic or that any antibody which it might elicit does not react with the antigens of the mature virus. The observations reported in this communication accord with the hypothesis that prophage is a genetic structure.
format Text
id pubmed-2136394
institution National Center for Biotechnology Information
language English
publishDate 1954
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21363942008-04-17 THE NATURE OF PROPHAGE IN LYSOGENIC BACILLUS MEGATHERIUM Miller, Elizabeth M. Goebel, Walther F. J Exp Med Article 1. By complement-fixation tests it has been shown that the lysogenic and sensitive strains of B. megatherium share one or more antigenic components which are serologically related but not identical. 2. Bacilli of the lysogenic strain of B. megatherium, when grown under conditions such that little extracellular phage is produced, fail to evoke antibodies in rabbits which react either in complement-fixation or neutralization tests with purified megatherium T phage. From this it must be concluded either that prophage is not antigenic or that any antibody which it might elicit does not react with the antigens of the mature virus. The observations reported in this communication accord with the hypothesis that prophage is a genetic structure. The Rockefeller University Press 1954-11-30 /pmc/articles/PMC2136394/ /pubmed/13211912 Text en Copyright © Copyright, 1954, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Miller, Elizabeth M.
Goebel, Walther F.
THE NATURE OF PROPHAGE IN LYSOGENIC BACILLUS MEGATHERIUM
title THE NATURE OF PROPHAGE IN LYSOGENIC BACILLUS MEGATHERIUM
title_full THE NATURE OF PROPHAGE IN LYSOGENIC BACILLUS MEGATHERIUM
title_fullStr THE NATURE OF PROPHAGE IN LYSOGENIC BACILLUS MEGATHERIUM
title_full_unstemmed THE NATURE OF PROPHAGE IN LYSOGENIC BACILLUS MEGATHERIUM
title_short THE NATURE OF PROPHAGE IN LYSOGENIC BACILLUS MEGATHERIUM
title_sort nature of prophage in lysogenic bacillus megatherium
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136394/
https://www.ncbi.nlm.nih.gov/pubmed/13211912
work_keys_str_mv AT millerelizabethm thenatureofprophageinlysogenicbacillusmegatherium
AT goebelwaltherf thenatureofprophageinlysogenicbacillusmegatherium
AT millerelizabethm natureofprophageinlysogenicbacillusmegatherium
AT goebelwaltherf natureofprophageinlysogenicbacillusmegatherium

Ejemplares similares