RELATION OF CERTAIN ENDOCRINE DISTURBANCES TO SUSCEPTIBILITY OF GOLDEN SYRIAN HAMSTER TO EXPERIMENTAL POLIOMYELITIS

Alterations in susceptibility of the Syrian hamster to poliomyelitis virus (MEF1) inoculated intracerebrally appeared closely related to seasonal changes and experimental disturbances in the adreno-testes equilibrium. Enhanced susceptibility coincided with seasonal enlargement of adrenals, followed...

Descripción completa

Detalles Bibliográficos
Autores principales: Teodoru, Constantin V., Shwartzman, Gregory
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1954
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136395/
https://www.ncbi.nlm.nih.gov/pubmed/13211914
_version_ 1782143117214875648
author Teodoru, Constantin V.
Shwartzman, Gregory
author_facet Teodoru, Constantin V.
Shwartzman, Gregory
author_sort Teodoru, Constantin V.
collection PubMed
description Alterations in susceptibility of the Syrian hamster to poliomyelitis virus (MEF1) inoculated intracerebrally appeared closely related to seasonal changes and experimental disturbances in the adreno-testes equilibrium. Enhanced susceptibility coincided with seasonal enlargement of adrenals, followed cortisone and DOCA treatment and appeared during the initial postorchiectomy period. Increased resistance occurred incidentally to adrenalectomy, seasonal diminution in adrenal weight, testosterone overdosage, and testicular hypertrophy induced by treatment with GTH or chorionic gonadotrophin. The effect of certain hormonal interactions, the interference of conditioning factors and the role of compensatory reactions are discussed.
format Text
id pubmed-2136395
institution National Center for Biotechnology Information
language English
publishDate 1954
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21363952008-04-17 RELATION OF CERTAIN ENDOCRINE DISTURBANCES TO SUSCEPTIBILITY OF GOLDEN SYRIAN HAMSTER TO EXPERIMENTAL POLIOMYELITIS Teodoru, Constantin V. Shwartzman, Gregory J Exp Med Article Alterations in susceptibility of the Syrian hamster to poliomyelitis virus (MEF1) inoculated intracerebrally appeared closely related to seasonal changes and experimental disturbances in the adreno-testes equilibrium. Enhanced susceptibility coincided with seasonal enlargement of adrenals, followed cortisone and DOCA treatment and appeared during the initial postorchiectomy period. Increased resistance occurred incidentally to adrenalectomy, seasonal diminution in adrenal weight, testosterone overdosage, and testicular hypertrophy induced by treatment with GTH or chorionic gonadotrophin. The effect of certain hormonal interactions, the interference of conditioning factors and the role of compensatory reactions are discussed. The Rockefeller University Press 1954-11-30 /pmc/articles/PMC2136395/ /pubmed/13211914 Text en Copyright © Copyright, 1954, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Teodoru, Constantin V.
Shwartzman, Gregory
RELATION OF CERTAIN ENDOCRINE DISTURBANCES TO SUSCEPTIBILITY OF GOLDEN SYRIAN HAMSTER TO EXPERIMENTAL POLIOMYELITIS
title RELATION OF CERTAIN ENDOCRINE DISTURBANCES TO SUSCEPTIBILITY OF GOLDEN SYRIAN HAMSTER TO EXPERIMENTAL POLIOMYELITIS
title_full RELATION OF CERTAIN ENDOCRINE DISTURBANCES TO SUSCEPTIBILITY OF GOLDEN SYRIAN HAMSTER TO EXPERIMENTAL POLIOMYELITIS
title_fullStr RELATION OF CERTAIN ENDOCRINE DISTURBANCES TO SUSCEPTIBILITY OF GOLDEN SYRIAN HAMSTER TO EXPERIMENTAL POLIOMYELITIS
title_full_unstemmed RELATION OF CERTAIN ENDOCRINE DISTURBANCES TO SUSCEPTIBILITY OF GOLDEN SYRIAN HAMSTER TO EXPERIMENTAL POLIOMYELITIS
title_short RELATION OF CERTAIN ENDOCRINE DISTURBANCES TO SUSCEPTIBILITY OF GOLDEN SYRIAN HAMSTER TO EXPERIMENTAL POLIOMYELITIS
title_sort relation of certain endocrine disturbances to susceptibility of golden syrian hamster to experimental poliomyelitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136395/
https://www.ncbi.nlm.nih.gov/pubmed/13211914
work_keys_str_mv AT teodoruconstantinv relationofcertainendocrinedisturbancestosusceptibilityofgoldensyrianhamstertoexperimentalpoliomyelitis
AT shwartzmangregory relationofcertainendocrinedisturbancestosusceptibilityofgoldensyrianhamstertoexperimentalpoliomyelitis

Ejemplares similares