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STUDIES ON THE IMMUNOLOGICAL RESPONSE TO FOREIGN TUMOR TRANSPLANTS IN THE MOUSE : III. CHANGES IN THE WEIGHT, AND CONTENT OF NUCLEIC ACIDS AND PROTEIN, OF HOST LYMPHOID TISSUES
A study was made of variation in weight of the host lymph nodes, spleen, and thymus, after implantation of transplantable tumors in susceptible and See PDF for Structure non-susceptible hosts. The lymph nodes and spleens of non-susceptible hosts increased in weight during the period when the organs...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1955
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136502/ https://www.ncbi.nlm.nih.gov/pubmed/13242743 |
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author | Andreini, P. Drasher, M. L. Mitchison, N. A. |
author_facet | Andreini, P. Drasher, M. L. Mitchison, N. A. |
author_sort | Andreini, P. |
collection | PubMed |
description | A study was made of variation in weight of the host lymph nodes, spleen, and thymus, after implantation of transplantable tumors in susceptible and See PDF for Structure non-susceptible hosts. The lymph nodes and spleens of non-susceptible hosts increased in weight during the period when the organs were participating in the immunological response, though an increase also took place in susceptible hosts. Variations in protein nitrogen and pentose- and desoxypentosenucleic acid of the draining lymph nodes of non-susceptible mice were also studied. The protein nitrogen content increased with the weight of the nodes. Increase in the PNA/DNA ratio occurred while the lymph node cells were engaged in production of antibody. Increase in the PNA/DNA ratio was interpreted as an increase in PNA per cell, and therefore of the rate of protein synthesis. |
format | Text |
id | pubmed-2136502 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1955 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21365022008-04-17 STUDIES ON THE IMMUNOLOGICAL RESPONSE TO FOREIGN TUMOR TRANSPLANTS IN THE MOUSE : III. CHANGES IN THE WEIGHT, AND CONTENT OF NUCLEIC ACIDS AND PROTEIN, OF HOST LYMPHOID TISSUES Andreini, P. Drasher, M. L. Mitchison, N. A. J Exp Med Article A study was made of variation in weight of the host lymph nodes, spleen, and thymus, after implantation of transplantable tumors in susceptible and See PDF for Structure non-susceptible hosts. The lymph nodes and spleens of non-susceptible hosts increased in weight during the period when the organs were participating in the immunological response, though an increase also took place in susceptible hosts. Variations in protein nitrogen and pentose- and desoxypentosenucleic acid of the draining lymph nodes of non-susceptible mice were also studied. The protein nitrogen content increased with the weight of the nodes. Increase in the PNA/DNA ratio occurred while the lymph node cells were engaged in production of antibody. Increase in the PNA/DNA ratio was interpreted as an increase in PNA per cell, and therefore of the rate of protein synthesis. The Rockefeller University Press 1955-08-01 /pmc/articles/PMC2136502/ /pubmed/13242743 Text en Copyright © Copyright, 1955, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Andreini, P. Drasher, M. L. Mitchison, N. A. STUDIES ON THE IMMUNOLOGICAL RESPONSE TO FOREIGN TUMOR TRANSPLANTS IN THE MOUSE : III. CHANGES IN THE WEIGHT, AND CONTENT OF NUCLEIC ACIDS AND PROTEIN, OF HOST LYMPHOID TISSUES |
title | STUDIES ON THE IMMUNOLOGICAL RESPONSE TO FOREIGN TUMOR TRANSPLANTS IN THE MOUSE : III. CHANGES IN THE WEIGHT, AND CONTENT OF NUCLEIC ACIDS AND PROTEIN, OF HOST LYMPHOID TISSUES |
title_full | STUDIES ON THE IMMUNOLOGICAL RESPONSE TO FOREIGN TUMOR TRANSPLANTS IN THE MOUSE : III. CHANGES IN THE WEIGHT, AND CONTENT OF NUCLEIC ACIDS AND PROTEIN, OF HOST LYMPHOID TISSUES |
title_fullStr | STUDIES ON THE IMMUNOLOGICAL RESPONSE TO FOREIGN TUMOR TRANSPLANTS IN THE MOUSE : III. CHANGES IN THE WEIGHT, AND CONTENT OF NUCLEIC ACIDS AND PROTEIN, OF HOST LYMPHOID TISSUES |
title_full_unstemmed | STUDIES ON THE IMMUNOLOGICAL RESPONSE TO FOREIGN TUMOR TRANSPLANTS IN THE MOUSE : III. CHANGES IN THE WEIGHT, AND CONTENT OF NUCLEIC ACIDS AND PROTEIN, OF HOST LYMPHOID TISSUES |
title_short | STUDIES ON THE IMMUNOLOGICAL RESPONSE TO FOREIGN TUMOR TRANSPLANTS IN THE MOUSE : III. CHANGES IN THE WEIGHT, AND CONTENT OF NUCLEIC ACIDS AND PROTEIN, OF HOST LYMPHOID TISSUES |
title_sort | studies on the immunological response to foreign tumor transplants in the mouse : iii. changes in the weight, and content of nucleic acids and protein, of host lymphoid tissues |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136502/ https://www.ncbi.nlm.nih.gov/pubmed/13242743 |
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