AMINO ACID COMPOSITION AND ELECTROPHORETIC PROPERTIES OF HYPERTENSIN I

A preparation of hypertensin I was purified by countercurrent distribution and was shown to migrate as a single component in starch blocks at pH 9.3 and 4.2. It had an isoelectric point of 7.7. Quantitative analysis by ion exchange column chromatography showed eight amino acids in approximately unim...

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Detalles Bibliográficos
Autores principales: Skeggs, Leonard T., Marsh, Walton H., Kahn, Joseph R., Shumway, Norman P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1955
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136516/
https://www.ncbi.nlm.nih.gov/pubmed/13263485
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author Skeggs, Leonard T.
Marsh, Walton H.
Kahn, Joseph R.
Shumway, Norman P.
author_facet Skeggs, Leonard T.
Marsh, Walton H.
Kahn, Joseph R.
Shumway, Norman P.
author_sort Skeggs, Leonard T.
collection PubMed
description A preparation of hypertensin I was purified by countercurrent distribution and was shown to migrate as a single component in starch blocks at pH 9.3 and 4.2. It had an isoelectric point of 7.7. Quantitative analysis by ion exchange column chromatography showed eight amino acids in approximately unimolar proportion: aspartic, proline, valine, isoleucine, leucine, tyrosine, phenylalanine, and arginine. There were in addition two moles of histidine.
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spelling pubmed-21365162008-04-17 AMINO ACID COMPOSITION AND ELECTROPHORETIC PROPERTIES OF HYPERTENSIN I Skeggs, Leonard T. Marsh, Walton H. Kahn, Joseph R. Shumway, Norman P. J Exp Med Article A preparation of hypertensin I was purified by countercurrent distribution and was shown to migrate as a single component in starch blocks at pH 9.3 and 4.2. It had an isoelectric point of 7.7. Quantitative analysis by ion exchange column chromatography showed eight amino acids in approximately unimolar proportion: aspartic, proline, valine, isoleucine, leucine, tyrosine, phenylalanine, and arginine. There were in addition two moles of histidine. The Rockefeller University Press 1955-09-30 /pmc/articles/PMC2136516/ /pubmed/13263485 Text en Copyright © Copyright, 1955, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Skeggs, Leonard T.
Marsh, Walton H.
Kahn, Joseph R.
Shumway, Norman P.
AMINO ACID COMPOSITION AND ELECTROPHORETIC PROPERTIES OF HYPERTENSIN I
title AMINO ACID COMPOSITION AND ELECTROPHORETIC PROPERTIES OF HYPERTENSIN I
title_full AMINO ACID COMPOSITION AND ELECTROPHORETIC PROPERTIES OF HYPERTENSIN I
title_fullStr AMINO ACID COMPOSITION AND ELECTROPHORETIC PROPERTIES OF HYPERTENSIN I
title_full_unstemmed AMINO ACID COMPOSITION AND ELECTROPHORETIC PROPERTIES OF HYPERTENSIN I
title_short AMINO ACID COMPOSITION AND ELECTROPHORETIC PROPERTIES OF HYPERTENSIN I
title_sort amino acid composition and electrophoretic properties of hypertensin i
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136516/
https://www.ncbi.nlm.nih.gov/pubmed/13263485
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