LYSIS OF T(4) PHAGE BY THE SPECIFIC LIPOCARBOHYDRATE OF PHASE II SHIGELLA SONNEI

When the specific lipocarbohydrate of Phase II Sh. sonnei and T(4) phage react in vitro, the virus is rapidly inactivated and the content of the viral membrane is released into the surrounding medium. The reaction between phage and lipocarbohydrate proceeds only in the presence of a lipide constitue...

Descripción completa

Detalles Bibliográficos
Autores principales: Jesaitis, Margeris A., Goebel, Walther F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1955
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136540/
https://www.ncbi.nlm.nih.gov/pubmed/13271686
_version_ 1782143142992019456
author Jesaitis, Margeris A.
Goebel, Walther F.
author_facet Jesaitis, Margeris A.
Goebel, Walther F.
author_sort Jesaitis, Margeris A.
collection PubMed
description When the specific lipocarbohydrate of Phase II Sh. sonnei and T(4) phage react in vitro, the virus is rapidly inactivated and the content of the viral membrane is released into the surrounding medium. The reaction between phage and lipocarbohydrate proceeds only in the presence of a lipide constituent which can be extracted from the polysaccharide, rendering the latter inactive, and which can be replaced by certain fatty acids. It has been suggested that the lipocarbohydrate is the receptor substance of the Phase II bacillus which specifically combines with and brings about disintegration of the virus when the latter infects the host cell.
format Text
id pubmed-2136540
institution National Center for Biotechnology Information
language English
publishDate 1955
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21365402008-04-17 LYSIS OF T(4) PHAGE BY THE SPECIFIC LIPOCARBOHYDRATE OF PHASE II SHIGELLA SONNEI Jesaitis, Margeris A. Goebel, Walther F. J Exp Med Article When the specific lipocarbohydrate of Phase II Sh. sonnei and T(4) phage react in vitro, the virus is rapidly inactivated and the content of the viral membrane is released into the surrounding medium. The reaction between phage and lipocarbohydrate proceeds only in the presence of a lipide constituent which can be extracted from the polysaccharide, rendering the latter inactive, and which can be replaced by certain fatty acids. It has been suggested that the lipocarbohydrate is the receptor substance of the Phase II bacillus which specifically combines with and brings about disintegration of the virus when the latter infects the host cell. The Rockefeller University Press 1955-11-30 /pmc/articles/PMC2136540/ /pubmed/13271686 Text en Copyright © Copyright, 1955, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Jesaitis, Margeris A.
Goebel, Walther F.
LYSIS OF T(4) PHAGE BY THE SPECIFIC LIPOCARBOHYDRATE OF PHASE II SHIGELLA SONNEI
title LYSIS OF T(4) PHAGE BY THE SPECIFIC LIPOCARBOHYDRATE OF PHASE II SHIGELLA SONNEI
title_full LYSIS OF T(4) PHAGE BY THE SPECIFIC LIPOCARBOHYDRATE OF PHASE II SHIGELLA SONNEI
title_fullStr LYSIS OF T(4) PHAGE BY THE SPECIFIC LIPOCARBOHYDRATE OF PHASE II SHIGELLA SONNEI
title_full_unstemmed LYSIS OF T(4) PHAGE BY THE SPECIFIC LIPOCARBOHYDRATE OF PHASE II SHIGELLA SONNEI
title_short LYSIS OF T(4) PHAGE BY THE SPECIFIC LIPOCARBOHYDRATE OF PHASE II SHIGELLA SONNEI
title_sort lysis of t(4) phage by the specific lipocarbohydrate of phase ii shigella sonnei
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136540/
https://www.ncbi.nlm.nih.gov/pubmed/13271686
work_keys_str_mv AT jesaitismargerisa lysisoft4phagebythespecificlipocarbohydrateofphaseiishigellasonnei
AT goebelwaltherf lysisoft4phagebythespecificlipocarbohydrateofphaseiishigellasonnei

Ejemplares similares